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Identification of immunogenic determinants of the spike protein of SARS-like coronavirus

Bat SARS-like coronavirus (SL-CoV) has a genome organization almost identical to that of SARS-CoV, but the N-terminus of the Spike (S) proteins, which interacts with host receptor and is a major target of neutralizing antibodies against CoVs, of the two viruses has only 63–64% sequence identity. Alt...

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Detalles Bibliográficos
Autores principales: Zhou, Peng, Han, Zhenggang, Wang, Lin-Fa, Shi, Zhengli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SP Wuhan Institute of Virology, CAS 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090416/
https://www.ncbi.nlm.nih.gov/pubmed/23575730
http://dx.doi.org/10.1007/s12250-013-3292-y