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Global analysis of an epidemic model with vaccination

In this paper, an epidemic dynamical model with vaccination is proposed. Vaccination of both newborn and susceptible is included in the present model. The impact of the vaccination strategy with the vaccine efficacy is explored. In particular, the model exhibits backward bifurcations under the vacci...

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Detalles Bibliográficos
Autores principales: Cai, Li-Ming, Li, Zhaoqing, Song, Xinyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090535/
https://www.ncbi.nlm.nih.gov/pubmed/32218713
http://dx.doi.org/10.1007/s12190-017-1124-1
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author Cai, Li-Ming
Li, Zhaoqing
Song, Xinyu
author_facet Cai, Li-Ming
Li, Zhaoqing
Song, Xinyu
author_sort Cai, Li-Ming
collection PubMed
description In this paper, an epidemic dynamical model with vaccination is proposed. Vaccination of both newborn and susceptible is included in the present model. The impact of the vaccination strategy with the vaccine efficacy is explored. In particular, the model exhibits backward bifurcations under the vaccination level, and bistability occurrence can be observed. Mathematically, a bifurcation analysis is performed, and the conditions ensuring that the system exhibits backward bifurcation are provided. The global dynamics of the equilibrium in the model are also investigated. Numerical simulations are also conducted to confirm and extend the analytic results.
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spelling pubmed-70905352020-03-24 Global analysis of an epidemic model with vaccination Cai, Li-Ming Li, Zhaoqing Song, Xinyu J Appl Math Comput Original Research In this paper, an epidemic dynamical model with vaccination is proposed. Vaccination of both newborn and susceptible is included in the present model. The impact of the vaccination strategy with the vaccine efficacy is explored. In particular, the model exhibits backward bifurcations under the vaccination level, and bistability occurrence can be observed. Mathematically, a bifurcation analysis is performed, and the conditions ensuring that the system exhibits backward bifurcation are provided. The global dynamics of the equilibrium in the model are also investigated. Numerical simulations are also conducted to confirm and extend the analytic results. Springer Berlin Heidelberg 2017-07-21 2018 /pmc/articles/PMC7090535/ /pubmed/32218713 http://dx.doi.org/10.1007/s12190-017-1124-1 Text en © Korean Society for Computational and Applied Mathematics 2017 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Original Research
Cai, Li-Ming
Li, Zhaoqing
Song, Xinyu
Global analysis of an epidemic model with vaccination
title Global analysis of an epidemic model with vaccination
title_full Global analysis of an epidemic model with vaccination
title_fullStr Global analysis of an epidemic model with vaccination
title_full_unstemmed Global analysis of an epidemic model with vaccination
title_short Global analysis of an epidemic model with vaccination
title_sort global analysis of an epidemic model with vaccination
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090535/
https://www.ncbi.nlm.nih.gov/pubmed/32218713
http://dx.doi.org/10.1007/s12190-017-1124-1
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