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Global analysis of an epidemic model with vaccination
In this paper, an epidemic dynamical model with vaccination is proposed. Vaccination of both newborn and susceptible is included in the present model. The impact of the vaccination strategy with the vaccine efficacy is explored. In particular, the model exhibits backward bifurcations under the vacci...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090535/ https://www.ncbi.nlm.nih.gov/pubmed/32218713 http://dx.doi.org/10.1007/s12190-017-1124-1 |
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author | Cai, Li-Ming Li, Zhaoqing Song, Xinyu |
author_facet | Cai, Li-Ming Li, Zhaoqing Song, Xinyu |
author_sort | Cai, Li-Ming |
collection | PubMed |
description | In this paper, an epidemic dynamical model with vaccination is proposed. Vaccination of both newborn and susceptible is included in the present model. The impact of the vaccination strategy with the vaccine efficacy is explored. In particular, the model exhibits backward bifurcations under the vaccination level, and bistability occurrence can be observed. Mathematically, a bifurcation analysis is performed, and the conditions ensuring that the system exhibits backward bifurcation are provided. The global dynamics of the equilibrium in the model are also investigated. Numerical simulations are also conducted to confirm and extend the analytic results. |
format | Online Article Text |
id | pubmed-7090535 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-70905352020-03-24 Global analysis of an epidemic model with vaccination Cai, Li-Ming Li, Zhaoqing Song, Xinyu J Appl Math Comput Original Research In this paper, an epidemic dynamical model with vaccination is proposed. Vaccination of both newborn and susceptible is included in the present model. The impact of the vaccination strategy with the vaccine efficacy is explored. In particular, the model exhibits backward bifurcations under the vaccination level, and bistability occurrence can be observed. Mathematically, a bifurcation analysis is performed, and the conditions ensuring that the system exhibits backward bifurcation are provided. The global dynamics of the equilibrium in the model are also investigated. Numerical simulations are also conducted to confirm and extend the analytic results. Springer Berlin Heidelberg 2017-07-21 2018 /pmc/articles/PMC7090535/ /pubmed/32218713 http://dx.doi.org/10.1007/s12190-017-1124-1 Text en © Korean Society for Computational and Applied Mathematics 2017 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Original Research Cai, Li-Ming Li, Zhaoqing Song, Xinyu Global analysis of an epidemic model with vaccination |
title | Global analysis of an epidemic model with vaccination |
title_full | Global analysis of an epidemic model with vaccination |
title_fullStr | Global analysis of an epidemic model with vaccination |
title_full_unstemmed | Global analysis of an epidemic model with vaccination |
title_short | Global analysis of an epidemic model with vaccination |
title_sort | global analysis of an epidemic model with vaccination |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090535/ https://www.ncbi.nlm.nih.gov/pubmed/32218713 http://dx.doi.org/10.1007/s12190-017-1124-1 |
work_keys_str_mv | AT cailiming globalanalysisofanepidemicmodelwithvaccination AT lizhaoqing globalanalysisofanepidemicmodelwithvaccination AT songxinyu globalanalysisofanepidemicmodelwithvaccination |