Cargando…

Two pathways of costimulation through CD28

CD28 is recognized as the primary costimulatory molecule involved in the activation of naïve T cells. However, the biochemical signaling pathways that are activated by CD28 and how these pathways are integrated with TCR signaling are still not understood. We have recently shown that there are at lea...

Descripción completa

Detalles Bibliográficos
Autores principales:	Miller, Jim, Baker, Christina, Cook, Kevin, Graf, Beth, Sanchez-Lockhart, Mariano, Sharp, Katherine, Wang, Xia, Yang, Barbara, Yoshida, Takeshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Humana Press Inc 2009
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7091045/ https://www.ncbi.nlm.nih.gov/pubmed/19214786 http://dx.doi.org/10.1007/s12026-009-8097-6

Ejemplares similares

CD28, Costimulator or Agonist Receptor?
por: Margulies, David H.
Publicado: (2003)

Membrane Rafts in T Cell Activation: A Spotlight on CD28 Costimulation
por: Zumerle, Sara, et al.
Publicado: (2017)

Sialic Acid Ligands of CD28 Suppress Costimulation of T Cells
por: Edgar, Landon J., et al.
Publicado: (2021)

A pathway of costimulation that prevents anergy in CD28- T cells: B7- independent costimulation of CD1-restricted T cells
Publicado: (1995)

Itk Negatively Regulates Induction of T Cell Proliferation by CD28 Costimulation
por: Liao, X. Charlene, et al.
Publicado: (1997)

CD28 Costimulation Regulates Genome-Wide Effects on Alternative Splicing
por: Butte, Manish J., et al.
Publicado: (2012)

CD28 Costimulation Is Required for In Vivo Induction of Peripheral Tolerance in CD8 T Cells
por: Vacchio, Melanie S., et al.
Publicado: (2003)

CD28 Costimulation of T Helper 1 Cells Enhances Cytokine Release In Vivo
por: Langenhorst, Daniela, et al.
Publicado: (2018)

CD28 costimulation drives tumor-infiltrating T cell glycolysis to promote inflammation
por: Beckermann, Kathryn E., et al.
Publicado: (2020)

B7-H5 costimulates human T cells via CD28H
por: Zhu, Yuwen, et al.
Publicado: (2013)

Costimulation of IL-2 Production through CD28 Is Dependent on the Size of Its Ligand
por: Lim, Hong-Sheng, et al.
Publicado: (2015)

Resting and anergic B cells are defective in CD28-dependent costimulation of naive CD4+ T cells
Publicado: (1994)

Modulation of NKT Cell Development by B7-CD28 Interaction: An Expanding Horizon for Costimulation
por: Zheng, Xincheng, et al.
Publicado: (2008)

Genomic profiling of T-cell activation suggests increased sensitivity of memory T cells to CD28 costimulation
por: Glinos, Dafni A., et al.
Publicado: (2020)

Systemic Administration of Acazicolcept, a Dual CD28 and Inducible T cell Costimulator Inhibitor, Ameliorates Experimental Autoimmune Uveitis
por: Wilson, Leslie, et al.
Publicado: (2023)

T Cell Receptor Signaling Can Directly Enhance the Avidity of CD28 Ligand Binding
por: Sanchez-Lockhart, Mariano, et al.
Publicado: (2014)

Costimulation of T Cell Activation by Integrin-associated Protein (CD47) Is an Adhesion-dependent, CD28-independent Signaling Pathway
por: Reinhold, Martina I., et al.
Publicado: (1997)

CD28-induced costimulation of T helper type 2 cells mediated by induction of responsiveness to interleukin 4
Publicado: (1993)

Proline Residues in Cd28 and the Src Homology (Sh)3 Domain of Lck Are Required for T Cell Costimulation
por: Holdorf, Amy D., et al.
Publicado: (1999)

CD28-independent, TRAF2-dependent Costimulation of Resting T Cells by 4-1BB Ligand
por: Saoulli, Katina, et al.
Publicado: (1998)

Differential regulation of motility and immune synapses by CD28/ CTLA-4 costimulation in effector and regulatory T cells
por: Dilek, Nahzli, et al.
Publicado: (2012)

1,25(OH)(2)D(3) Promotes the Efficacy of CD28 Costimulation Blockade by Abatacept
por: Gardner, David H., et al.
Publicado: (2015)

The engineered CD80 variant fusion therapeutic davoceticept combines checkpoint antagonism with conditional CD28 costimulation for anti-tumor immunity
por: Maurer, Mark F., et al.
Publicado: (2022)

CD28-independent Induction of T Helper Cells and Immunoglobulin Class Switches Requires Costimulation by the Heat-stable Antigen
por: Wu, Yan, et al.
Publicado: (1998)

Ndrg1 is a T-cell clonal anergy factor negatively regulated by CD28 costimulation and interleukin-2
por: Oh, Yu Mi, et al.
Publicado: (2015)

CD28 interaction with B7 costimulates primary allogeneic proliferative responses and cytotoxicity mediated by small, resting T lymphocytes
Publicado: (1992)

B7/CD28 in Central Tolerance: Costimulation Promotes Maturation of Regulatory T Cell Precursors and Prevents Their Clonal Deletion
por: Hinterberger, Maria, et al.
Publicado: (2011)

Role of CD28/B7 costimulation and IL-12/IL-10 interaction in the radiation-induced immune changes
por: Liu, Shu-Zheng, et al.
Publicado: (2001)

T Cell Receptor (TCR)-induced Death of Immature CD4(+)CD8(+) Thymocytes by Two Distinct Mechanisms Differing in Their Requirement for CD28 Costimulation: Implications for Negative Selection in the Thymus
por: Punt, Jennifer A., et al.
Publicado: (1997)

A short CD3/CD28 costimulation combined with IL-21 enhance the generation of human memory stem T cells for adoptive immunotherapy
por: Alvarez-Fernández, C., et al.
Publicado: (2016)

Route of 41BB/41BBL Costimulation Determines Effector Function of B7-H3-CAR.CD28ζ T Cells
por: Nguyen, Phuong, et al.
Publicado: (2020)

CD80 Costimulation Is Essential for the Induction of Airway Eosinophilia
por: Harris, Nicola, et al.
Publicado: (1997)

MRP1-CD28 bi-specific oligonucleotide aptamers: target costimulation to drug-resistant melanoma cancer stem cells
por: Soldevilla, Mario Martínez, et al.
Publicado: (2016)

Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation
Publicado: (1991)

T Cell Costimulation through CD28 Depends on Induction of the Bcl-xγ Isoform: Analysis of Bcl-xγ–deficient Mice
por: Ye, Qunrui, et al.
Publicado: (2002)

B7-CD28 costimulation unveils the hierarchy of tumor epitopes recognized by major histocompatibility complex class I-restricted CD8+ cytolytic T lymphocytes
Publicado: (1996)

OX40 costimulation by a chimeric antigen receptor abrogates CD28 and IL-2 induced IL-10 secretion by redirected CD4(+) T cells
por: Hombach, Andreas A., et al.
Publicado: (2012)

Costimulation to enhance the antitumor activity of CD19 eng T cells
por: Velasquez, Mireya, et al.
Publicado: (2015)

T Cell Mediated Antibody lnvariance in an Immune Response Against A Bacterial Carbohydrate Antigen Requires CD28/B7–1 Costimulation
por: Rademaekers, André, et al.
Publicado: (2001)

A Single Amino Acid Alteration in Cytoplasmic Domain Determines IL-2 Promoter Activation by Ligation of CD28 but Not Inducible Costimulator (ICOS)
por: Harada, Yohsuke, et al.
Publicado: (2003)

Cannot write session to /tmp/vufind_sessions/sess_v75p2j27cvp3b7tbggteuhps9c