Cargando…

Construction and genetic analysis of murine hepatitis virus strain A59 Nsp16 temperature sensitive mutant and the revertant virus

Coronaviruses (CoVs) are generally associated with respiratory and enteric infections and have long been recognized as important pathogens of livestock and companion animals. Mouse hepatitis virus (MHV) is a widely studied model system for Coronavirus replication and pathogenesis. In this study, we...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chang, Guo-hui, Luo, Bao-jun, Lu, Pin, Lin, Lei, Wu, Xiao-yan, Li, Jing, Hu, Yi, Zhu, Qing-yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SP Wuhan Institute of Virology, CAS 2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7091325/ https://www.ncbi.nlm.nih.gov/pubmed/21331887 http://dx.doi.org/10.1007/s12250-011-3145-x

Ejemplares similares

Murine hepatitis virus nsp4 N258T mutants are not temperature-sensitive
por: Beachboard, Dia C., et al.
Publicado: (2013)

Temperature-sensitive mutants of mouse hepatitis virus strain A59: Isolation, characterization and neuropathogenic properties
por: Koolen, Marck J.M., et al.
Publicado: (1983)

Physico-chemical properties of murine hepatitis virus, strain A59
por: Daniel, C., et al.
Publicado: (1987)

Effects of Mutagenesis of Murine Hepatitis Virus NSP1 and NSP14 on Replication in Culture
por: Eckerle, Lance D., et al.
Publicado: (2006)

Murine Hepatitis Virus Exoribonuclease nsp14 Is Required for the Biogenesis of Viral Circular RNAs
por: Yang, Shaomin, et al.
Publicado: (2023)

Microheterogeneity of S-glycoprotein of mouse hepatitis virus temperature-sensitive mutants
por: Oleszak, Emilia L., et al.
Publicado: (1992)

Protection from lethal coronavirus infection by affinity-purified spike glycoprotein of murine hepatitis virus, strain A59
por: Daniel, Claude, et al.
Publicado: (1990)

MHV-A59 Orf1a Replicase Protein NSP7-NSP10 Processing in Replication
por: Deming, Damon J., et al.
Publicado: (2006)

Mutational Analysis of MHV-A59 Replicase Protein-NSP10
por: Donaldson, Eric F., et al.
Publicado: (2006)

In vivo growth of porcine reproductive and respiratory syndrome virus engineered nsp2 deletion mutants
por: Faaberg, Kay S., et al.
Publicado: (2010)

Immunogenic and antigenic analysis of recombinant NSP1 and NSP11 of PRRS virus
por: Contreras‐Luna, María Josefina, et al.
Publicado: (2022)

zfishbook: connecting you to a world of zebrafish revertible mutants
por: Clark, Karl J., et al.
Publicado: (2012)

Protein synthesis in cells infected by murine hepatitis viruses JHM and A59: Tryptic peptide analysis
por: Bond, C. W., et al.
Publicado: (1984)

Crystallization and diffraction analysis of the SARS coronavirus nsp10–nsp16 complex
por: Debarnot, Claire, et al.
Publicado: (2011)

Coronavirus Inhibitors Targeting nsp16
por: Omer, Ejlal A., et al.
Publicado: (2023)

Sindbis Virus nsP2 Endopeptidase
por: Strauss, Ellen G., et al.
Publicado: (2013)

Pathogenic murine coronaviruses II. Characterization of virus-specific proteins of murine coronaviruses JHMV and A59V
por: Bond, Clifford W., et al.
Publicado: (1979)

Substrate Specificity of SARS-CoV-2 Nsp10-Nsp16 Methyltransferase
por: Benoni, Roberto, et al.
Publicado: (2021)

Characterization of the cold-sensitive murine hepatitis virus mutants rescued from latently infected cells by cell fusion
por: Stohlman, Stephen A., et al.
Publicado: (1979)

Infidelity of SARS-CoV Nsp14-Exonuclease Mutant Virus Replication Is Revealed by Complete Genome Sequencing
por: Eckerle, Lance D., et al.
Publicado: (2010)

Effects of interleukin 17A (IL-17A) neutralization on murine hepatitis virus (MHV-A59) infection
por: Aparicio, José L., et al.
Publicado: (2017)

Identification of fragments binding to SARS-CoV-2 nsp10 reveals ligand-binding sites in conserved interfaces between nsp10 and nsp14/nsp16
por: Kozielski, Frank, et al.
Publicado: (2021)

Temperature-sensitive mutants of mouse hepatitis virus type 3 (MHV-3): isolation, biochemical and genetic characterization
por: Martin, J. -P., et al.
Publicado: (1988)

Virus persistence and recurring demyelination produced by a temperature-sensitive mutant of MHV-4
por: Knobler, Robert L., et al.
Publicado: (1982)

Mouse Hepatitis Virus Strain A59 RNA Polymerase Gene ORF 1a: Heterogeneity among MHV Strains
por: Bonilla, Pedro J., et al.
Publicado: (1994)

Chikungunya virus nsP1 interacts directly with nsP2 and modulates its ATPase activity
por: Kumar, Sameer, et al.
Publicado: (2018)

Mutagenesis of the murine hepatitis virus nsp1-coding region identifies residues important for protein processing, viral RNA synthesis, and viral replication
por: Brockway, Sarah M., et al.
Publicado: (2005)

SS148 and WZ16 inhibit the activities of nsp10-nsp16 complexes from all seven human pathogenic coronaviruses
por: Li, Fengling, et al.
Publicado: (2023)

Identification of novel mutations in the methyltransferase complex (Nsp10-Nsp16) of SARS-CoV-2
por: Azad, Gajendra Kumar
Publicado: (2020)

Comparison of Binding Site of Remdesivir and Its Metabolites with NSP12-NSP7-NSP8, and NSP3 of SARS CoV-2 Virus and Alternative Potential Drugs for COVID-19 Treatment
por: Jung, Lindsey S, et al.
Publicado: (2020)

Role of spleen macrophages in innate and acquired immune responses against mouse hepatitis virus strain A59.
por: Wijburg, O L, et al.
Publicado: (1997)

Attenuation of Mouse Hepatitis Virus by Deletion of the LLRKxGxKG Region of Nsp1
por: Lei, Lin, et al.
Publicado: (2013)

The NSP2 Proteins of Mouse Hepatitis Virus and Sars Coronavirus are Dispensable for Viral Replication
por: Graham, Rachel L., et al.
Publicado: (2006)

The virus-specific intracellular RNA species of two murine coronaviruses: MHV-A59 and MHV-JHM()
por: Leibowitz, Julian L., et al.
Publicado: (1981)

Targeting myeloid derived suppressor cells reverts immune suppression and sensitizes BRAF-mutant papillary thyroid cancer to MAPK inhibitors
por: Zhang, Peitao, et al.
Publicado: (2022)

Pathogenic murine coronaviruses III. Biological and biochemical characterization of temperature sensitive mutants of JHMV
por: Robb, James A., et al.
Publicado: (1979)

Crystal structure of SARS‐CoV‐2 nsp10–nsp16 in complex with small molecule inhibitors, SS148 and WZ16
por: Klima, Martin, et al.
Publicado: (2022)

The crystal structure of nsp10-nsp16 heterodimer from SARS-CoV-2 in complex with S-adenosylmethionine
por: Rosas-Lemus, Monica, et al.
Publicado: (2020)

Genetic analysis of revertants isolated from the rod-fragile fliF mutant of Salmonella
por: Komatsu, Hitomi, et al.
Publicado: (2016)

The peptide specificities of the autoantibodies elicited by mouse hepatitis virus A59
por: Duhalde-Vega, Maite, et al.
Publicado: (2006)

Cannot write session to /tmp/vufind_sessions/sess_a43vbc5ona4hqcto4gprq01er2