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Molecular mechanisms of coronavirus RNA capping and methylation

The 5′-cap structures of eukaryotic mRNAs are important for RNA stability, pre-mRNA splicing, mRNA export, and protein translation. Many viruses have evolved mechanisms for generating their own cap structures with methylation at the N7 position of the capped guanine and the ribose 2′-Oposition of th...

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Detalles Bibliográficos
Autores principales: Chen, Yu, Guo, Deyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7091378/
https://www.ncbi.nlm.nih.gov/pubmed/26847650
http://dx.doi.org/10.1007/s12250-016-3726-4