Significant alterations of biodistribution and immune responses in Balb/c mice administered with adenovirus targeted to CD40(+) cells

CD40 ligation has been shown to promote antigen-presenting functions of dendritic cells, which express CD40 receptor. Here we reported significantly altered biodistribution and immune responses with the use of CD40-targeted adenovirus. Compared with unmodified adenovirus 5, the CD40-targeted adenovi...

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Detalles Bibliográficos
Autores principales: Huang, D, Pereboev, A V, Korokhov, N, He, R, Larocque, L, Gravel, C, Jaentschke, B, Tocchi, M, Casley, W L, Lemieux, M, Curiel, D T, Chen, W, Li, X
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2007
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7091597/
https://www.ncbi.nlm.nih.gov/pubmed/18046426
http://dx.doi.org/10.1038/sj.gt.3303085

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