Virus PCR Assay Panels: An Alternative to the Mouse Antibody Production Test

Antibody production tests have traditionally been used to test biological materials for viral contamination. Now molecular biology techniques have emerged as an alternative. The authors compare MAP testing with PCR-based detection methods, focusing on differences in animal use, laboratory requiremen...

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Detalles Bibliográficos
Autores principales: Blank, Walter A., Henderson, Kenneth S., White, Lisa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2004
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7091613/
https://www.ncbi.nlm.nih.gov/pubmed/15235643
http://dx.doi.org/10.1038/laban0204-26
Descripción
Sumario:Antibody production tests have traditionally been used to test biological materials for viral contamination. Now molecular biology techniques have emerged as an alternative. The authors compare MAP testing with PCR-based detection methods, focusing on differences in animal use, laboratory requirements, sample size, and limits of detection.

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