Virus PCR Assay Panels: An Alternative to the Mouse Antibody Production Test

Antibody production tests have traditionally been used to test biological materials for viral contamination. Now molecular biology techniques have emerged as an alternative. The authors compare MAP testing with PCR-based detection methods, focusing on differences in animal use, laboratory requiremen...

Descripción completa

Detalles Bibliográficos
Autores principales: Blank, Walter A., Henderson, Kenneth S., White, Lisa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2004
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7091613/
https://www.ncbi.nlm.nih.gov/pubmed/15235643
http://dx.doi.org/10.1038/laban0204-26
_version_ 1783510038410690560
author Blank, Walter A.
Henderson, Kenneth S.
White, Lisa A.
author_facet Blank, Walter A.
Henderson, Kenneth S.
White, Lisa A.
author_sort Blank, Walter A.
collection PubMed
description Antibody production tests have traditionally been used to test biological materials for viral contamination. Now molecular biology techniques have emerged as an alternative. The authors compare MAP testing with PCR-based detection methods, focusing on differences in animal use, laboratory requirements, sample size, and limits of detection.
format Online
Article
Text
id pubmed-7091613
institution National Center for Biotechnology Information
language English
publishDate 2004
publisher Nature Publishing Group US
record_format MEDLINE/PubMed
spelling pubmed-70916132020-03-24 Virus PCR Assay Panels: An Alternative to the Mouse Antibody Production Test Blank, Walter A. Henderson, Kenneth S. White, Lisa A. Lab Anim (NY) Article Antibody production tests have traditionally been used to test biological materials for viral contamination. Now molecular biology techniques have emerged as an alternative. The authors compare MAP testing with PCR-based detection methods, focusing on differences in animal use, laboratory requirements, sample size, and limits of detection. Nature Publishing Group US 2004 /pmc/articles/PMC7091613/ /pubmed/15235643 http://dx.doi.org/10.1038/laban0204-26 Text en © Nature Publishing Group 2004 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Blank, Walter A.
Henderson, Kenneth S.
White, Lisa A.
Virus PCR Assay Panels: An Alternative to the Mouse Antibody Production Test
title Virus PCR Assay Panels: An Alternative to the Mouse Antibody Production Test
title_full Virus PCR Assay Panels: An Alternative to the Mouse Antibody Production Test
title_fullStr Virus PCR Assay Panels: An Alternative to the Mouse Antibody Production Test
title_full_unstemmed Virus PCR Assay Panels: An Alternative to the Mouse Antibody Production Test
title_short Virus PCR Assay Panels: An Alternative to the Mouse Antibody Production Test
title_sort virus pcr assay panels: an alternative to the mouse antibody production test
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7091613/
https://www.ncbi.nlm.nih.gov/pubmed/15235643
http://dx.doi.org/10.1038/laban0204-26
work_keys_str_mv AT blankwaltera viruspcrassaypanelsanalternativetothemouseantibodyproductiontest
AT hendersonkenneths viruspcrassaypanelsanalternativetothemouseantibodyproductiontest
AT whitelisaa viruspcrassaypanelsanalternativetothemouseantibodyproductiontest

Ejemplares similares