HSCT may lower leukemia risk in ELANE neutropenia: a before–after study from the French Severe Congenital Neutropenia Registry

ELANE neutropenia is associated with myelodysplasia and acute leukemia (MDS–AL), and severe infections. Because the MDS–AL risk has also been shown to be associated with exposure to GCSF, since 2005, in France, patients receiving high daily GCSF doses (>15 μg/kg/day) are eligible for HSCT, in add...

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Detalles Bibliográficos
Autores principales: Rotulo, Gioacchino Andrea, Beaupain, Blandine, Rialland, Fanny, Paillard, Catherine, Nachit, Ouahiba, Galambrun, Claire, Gandemer, Virginie, Bertrand, Yves, Neven, Benedicte, Dore, Eric, Moshous, Despina, Filhon, Bruno, Aladjdi, Nathalie, Sicre de Fontbrune, Flore, de la Tour, Regis Peffault, Ouachee, Marie, Bellanne-Chantelot, Christine, Dalle, Jean-Hugues, Donadieu, Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7091645/
https://www.ncbi.nlm.nih.gov/pubmed/31992846
http://dx.doi.org/10.1038/s41409-020-0800-1

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