Natural product juglone targets three key enzymes from Helicobacter pylori: inhibition assay with crystal structure characterization

AIM: To investigate the inhibition features of the natural product juglone (5-hydroxy-1,4-naphthoquinone) against the three key enzymes from Helicobacter pylori (cystathionine γ-synthase [HpCGS], malonyl-CoA:acyl carrier protein transacylase [HpFabD], and β-hydroxyacyl-ACP dehydratase [HpFabZ]). MET...

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Detalles Bibliográficos
Autores principales: Kong, Yun-hua, Zhang, Liang, Yang, Zheng-yi, Han, Cong, Hu, Li-hong, Jiang, Hua-liang, Shen, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7091819/
https://www.ncbi.nlm.nih.gov/pubmed/18565285
http://dx.doi.org/10.1111/j.1745-7254.2008.00808.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7091819/
https://www.ncbi.nlm.nih.gov/pubmed/18565285
http://dx.doi.org/10.1111/j.1745-7254.2008.00808.x

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