Multi-peaked adaptive landscape for chikungunya virus evolution predicts continued fitness optimization in Aedes albopictus mosquitoes

Host species-specific fitness landscapes largely determine the outcome of host switching during pathogen emergence. Using chikungunya virus (CHIKV) to study adaptation to a mosquito vector, we evaluated mutations associated with recently evolved sub-lineages. Multiple Aedes albopictus-adaptive fitne...

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Detalles Bibliográficos
Autores principales: Tsetsarkin, Konstantin A., Chen, Rubing, Yun, Ruimei, Rossi, Shannan L., Plante, Kenneth S., Guerbois, Mathilde, Forrester, Naomi, Perng, Guey Chuen, Sreekumar, Easwaran, Leal, Grace, Huang, Jing, Mukhopadhyay, Suchetana, Weaver, Scott C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7091890/
https://www.ncbi.nlm.nih.gov/pubmed/24933611
http://dx.doi.org/10.1038/ncomms5084

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