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Early Growth Response gene 1 (Egr-1) regulates HSV-1 ICP4 and ICP22 gene expression

The molecular mechanisms mediating herpes simplex virus type 1 (HSV-1) gene silencing during latent infection are not clear. Five copies of early growth response gene 1 (Egr-1) binding elements were identified in the intron of HSV-1 ICP22 (infected cell protein No. 22) gene, leading to the hypothesi...

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Detalles Bibliográficos
Autores principales: Bedadala, Gautam R, Pinnoji, Rajeswara C, Hsia, Shao-Chung V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092374/
https://www.ncbi.nlm.nih.gov/pubmed/17502875
http://dx.doi.org/10.1038/cr.2007.44