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Exacerbation of Chronic Obstructive Pulmonary Disease

Chronic obstructive pulmonary disease (COPD) is a disease with high prevalence and substantial associated economical burden. A significant determinant of quality of life, long-term survival, and health care costs is an acute exacerbation of COPD. Acute exacerbations are provoked by respiratory virus...

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Detalles Bibliográficos
Autores principales: Zhou, Xianghui, Li, Qingling, Zhou, Xincan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092375/
https://www.ncbi.nlm.nih.gov/pubmed/27352322
http://dx.doi.org/10.1007/s12013-015-0605-9
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author Zhou, Xianghui
Li, Qingling
Zhou, Xincan
author_facet Zhou, Xianghui
Li, Qingling
Zhou, Xincan
author_sort Zhou, Xianghui
collection PubMed
description Chronic obstructive pulmonary disease (COPD) is a disease with high prevalence and substantial associated economical burden. A significant determinant of quality of life, long-term survival, and health care costs is an acute exacerbation of COPD. Acute exacerbations are provoked by respiratory viruses, altered airway microbiome, and environmental factors. The current treatment options are limited. In order to develop specific therapeutic measures, it is important to understand how acute exacerbations evolve. This review focuses on pathophysiology of stable and exacerbated COPD.
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spelling pubmed-70923752020-03-24 Exacerbation of Chronic Obstructive Pulmonary Disease Zhou, Xianghui Li, Qingling Zhou, Xincan Cell Biochem Biophys Original Paper Chronic obstructive pulmonary disease (COPD) is a disease with high prevalence and substantial associated economical burden. A significant determinant of quality of life, long-term survival, and health care costs is an acute exacerbation of COPD. Acute exacerbations are provoked by respiratory viruses, altered airway microbiome, and environmental factors. The current treatment options are limited. In order to develop specific therapeutic measures, it is important to understand how acute exacerbations evolve. This review focuses on pathophysiology of stable and exacerbated COPD. Springer US 2015-05-23 2015 /pmc/articles/PMC7092375/ /pubmed/27352322 http://dx.doi.org/10.1007/s12013-015-0605-9 Text en © Springer Science+Business Media New York 2015 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Original Paper
Zhou, Xianghui
Li, Qingling
Zhou, Xincan
Exacerbation of Chronic Obstructive Pulmonary Disease
title Exacerbation of Chronic Obstructive Pulmonary Disease
title_full Exacerbation of Chronic Obstructive Pulmonary Disease
title_fullStr Exacerbation of Chronic Obstructive Pulmonary Disease
title_full_unstemmed Exacerbation of Chronic Obstructive Pulmonary Disease
title_short Exacerbation of Chronic Obstructive Pulmonary Disease
title_sort exacerbation of chronic obstructive pulmonary disease
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092375/
https://www.ncbi.nlm.nih.gov/pubmed/27352322
http://dx.doi.org/10.1007/s12013-015-0605-9
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