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Exacerbation of Chronic Obstructive Pulmonary Disease
Chronic obstructive pulmonary disease (COPD) is a disease with high prevalence and substantial associated economical burden. A significant determinant of quality of life, long-term survival, and health care costs is an acute exacerbation of COPD. Acute exacerbations are provoked by respiratory virus...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092375/ https://www.ncbi.nlm.nih.gov/pubmed/27352322 http://dx.doi.org/10.1007/s12013-015-0605-9 |
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author | Zhou, Xianghui Li, Qingling Zhou, Xincan |
author_facet | Zhou, Xianghui Li, Qingling Zhou, Xincan |
author_sort | Zhou, Xianghui |
collection | PubMed |
description | Chronic obstructive pulmonary disease (COPD) is a disease with high prevalence and substantial associated economical burden. A significant determinant of quality of life, long-term survival, and health care costs is an acute exacerbation of COPD. Acute exacerbations are provoked by respiratory viruses, altered airway microbiome, and environmental factors. The current treatment options are limited. In order to develop specific therapeutic measures, it is important to understand how acute exacerbations evolve. This review focuses on pathophysiology of stable and exacerbated COPD. |
format | Online Article Text |
id | pubmed-7092375 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Springer US |
record_format | MEDLINE/PubMed |
spelling | pubmed-70923752020-03-24 Exacerbation of Chronic Obstructive Pulmonary Disease Zhou, Xianghui Li, Qingling Zhou, Xincan Cell Biochem Biophys Original Paper Chronic obstructive pulmonary disease (COPD) is a disease with high prevalence and substantial associated economical burden. A significant determinant of quality of life, long-term survival, and health care costs is an acute exacerbation of COPD. Acute exacerbations are provoked by respiratory viruses, altered airway microbiome, and environmental factors. The current treatment options are limited. In order to develop specific therapeutic measures, it is important to understand how acute exacerbations evolve. This review focuses on pathophysiology of stable and exacerbated COPD. Springer US 2015-05-23 2015 /pmc/articles/PMC7092375/ /pubmed/27352322 http://dx.doi.org/10.1007/s12013-015-0605-9 Text en © Springer Science+Business Media New York 2015 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Original Paper Zhou, Xianghui Li, Qingling Zhou, Xincan Exacerbation of Chronic Obstructive Pulmonary Disease |
title | Exacerbation of Chronic Obstructive Pulmonary Disease |
title_full | Exacerbation of Chronic Obstructive Pulmonary Disease |
title_fullStr | Exacerbation of Chronic Obstructive Pulmonary Disease |
title_full_unstemmed | Exacerbation of Chronic Obstructive Pulmonary Disease |
title_short | Exacerbation of Chronic Obstructive Pulmonary Disease |
title_sort | exacerbation of chronic obstructive pulmonary disease |
topic | Original Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092375/ https://www.ncbi.nlm.nih.gov/pubmed/27352322 http://dx.doi.org/10.1007/s12013-015-0605-9 |
work_keys_str_mv | AT zhouxianghui exacerbationofchronicobstructivepulmonarydisease AT liqingling exacerbationofchronicobstructivepulmonarydisease AT zhouxincan exacerbationofchronicobstructivepulmonarydisease |