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Effect of episomally encoded DNA polymerases on chemically induced mutagenesis at the hisG46 target in Ames test
BACKGROUND: The standard Ames test strains owe their high sensitivity to chemical and physical mutagens to the episomal Y-family DNA polymerase RI encoded by the mucAB operon. The S. typhimurium test strains carry also another related samAB operon on a 60-kDa cryptic plasmid. In contrast to the chro...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092418/ https://www.ncbi.nlm.nih.gov/pubmed/32211083 http://dx.doi.org/10.1186/s41021-020-00154-2 |