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Effect of nicastrin on hepatocellular carcinoma proliferation and apoptosis through PI3K/AKT signalling pathway modulation

BACKGROUND: Increasing evidence has proven that the γ-secretase complex plays significant roles in the carcinogenesis of malignancies. However, the independent effect of nicastrin (NCSTN), the largest constituent of the γ-secretase complex, on the progression of hepatocellular carcinoma (HCC) remain...

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Detalles Bibliográficos
Autores principales:	Wang, Xicheng, Wang, Xining, Xu, Yunxiuxiu, Yan, Maolin, Li, Wenxin, Chen, Jie, Chen, Tao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092570/ https://www.ncbi.nlm.nih.gov/pubmed/32226312 http://dx.doi.org/10.1186/s12935-020-01172-4

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