Elav-Mediated Exon Skipping and Alternative Polyadenylation of the Dscam1 Gene Are Required for Axon Outgrowth

Many metazoan genes express alternative long 3′ UTR isoforms in the nervous system, but their functions remain largely unclear. In Drosophila melanogaster, the Dscam1 gene generates short and long (Dscam1-L) 3′ UTR isoforms because of alternative polyadenylation (APA). Here, we found that the RNA-bi...

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Detalles Bibliográficos
Autores principales: Zhang, Zhiping, So, Kevin, Peterson, Ryan, Bauer, Matthew, Ng, Henry, Zhang, Yong, Kim, Jung Hwan, Kidd, Thomas, Miura, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092717/
https://www.ncbi.nlm.nih.gov/pubmed/31242415
http://dx.doi.org/10.1016/j.celrep.2019.05.083

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