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Inhibition of GSK3 Represses the Expression of Retinoic Acid Synthetic Enzyme ALDH1A2 via Wnt/β-Catenin Signaling in WiT49 Cells

Organogenesis, including renal development, requires an appropriate retinoic acid concentration, which is established by differential expression of aldehyde dehydrogenase 1 family member A2 (ALDH1A2) and cytochrome P450 family 26 subfamily A/B/C member 1 (CYP26A1/B1/C1). In the fetal kidney, ALDH1A2...

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Detalles Bibliográficos
Autores principales: Li, Yifan, Gong, Hui, Ding, Jiangfeng, Zhao, Fujuan, Du, Jihui, Wan, Jun, Zhang, Juan, Liu, Shaoxiong, Li, Jing, Wang, Lei, Zhou, Bei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092725/
https://www.ncbi.nlm.nih.gov/pubmed/32258025
http://dx.doi.org/10.3389/fcell.2020.00094

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