Interleukin-17A/F1 Deficiency Reduces Antimicrobial Gene Expression and Contributes to Microbiome Alterations in Intestines of Japanese medaka (Oryzias latipes)

In mammals, interleukin (IL)-17A and F are hallmark inflammatory cytokines that play key roles in protection against infection and intestinal mucosal immunity. In the gastrointestinal tract (GI), the induction of antimicrobial peptide (AMP) production via Paneth cells is a fundamental role of IL-17A...

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Detalles Bibliográficos
Autores principales: Okamura, Yo, Morimoto, Natsuki, Ikeda, Daisuke, Mizusawa, Nanami, Watabe, Shugo, Miyanishi, Hiroshi, Saeki, Yuichi, Takeyama, Haruko, Aoki, Takashi, Kinoshita, Masato, Kono, Tomoya, Sakai, Masahiro, Hikima, Jun-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092794/
https://www.ncbi.nlm.nih.gov/pubmed/32256492
http://dx.doi.org/10.3389/fimmu.2020.00425

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