A Novel Coronavirus from Patients with Pneumonia in China, 2019

In December 2019, a cluster of patients with pneumonia of unknown cause was linked to a seafood wholesale market in Wuhan, China. A previously unknown betacoronavirus was discovered through the use of unbiased sequencing in samples from patients with pneumonia. Human airway epithelial cells were use...

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Autores principales: Zhu, Na, Zhang, Dingyu, Wang, Wenling, Li, Xingwang, Yang, Bo, Song, Jingdong, Zhao, Xiang, Huang, Baoying, Shi, Weifeng, Lu, Roujian, Niu, Peihua, Zhan, Faxian, Ma, Xuejun, Wang, Dayan, Xu, Wenbo, Wu, Guizhen, Gao, George F., Tan, Wenjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Massachusetts Medical Society 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092803/
https://www.ncbi.nlm.nih.gov/pubmed/31978945
http://dx.doi.org/10.1056/NEJMoa2001017
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author Zhu, Na
Zhang, Dingyu
Wang, Wenling
Li, Xingwang
Yang, Bo
Song, Jingdong
Zhao, Xiang
Huang, Baoying
Shi, Weifeng
Lu, Roujian
Niu, Peihua
Zhan, Faxian
Ma, Xuejun
Wang, Dayan
Xu, Wenbo
Wu, Guizhen
Gao, George F.
Tan, Wenjie
author_facet Zhu, Na
Zhang, Dingyu
Wang, Wenling
Li, Xingwang
Yang, Bo
Song, Jingdong
Zhao, Xiang
Huang, Baoying
Shi, Weifeng
Lu, Roujian
Niu, Peihua
Zhan, Faxian
Ma, Xuejun
Wang, Dayan
Xu, Wenbo
Wu, Guizhen
Gao, George F.
Tan, Wenjie
author_sort Zhu, Na
collection PubMed
description In December 2019, a cluster of patients with pneumonia of unknown cause was linked to a seafood wholesale market in Wuhan, China. A previously unknown betacoronavirus was discovered through the use of unbiased sequencing in samples from patients with pneumonia. Human airway epithelial cells were used to isolate a novel coronavirus, named 2019-nCoV, which formed a clade within the subgenus sarbecovirus, Orthocoronavirinae subfamily. Different from both MERS-CoV and SARS-CoV, 2019-nCoV is the seventh member of the family of coronaviruses that infect humans. Enhanced surveillance and further investigation are ongoing. (Funded by the National Key Research and Development Program of China and the National Major Project for Control and Prevention of Infectious Disease in China.)
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spelling pubmed-70928032020-04-02 A Novel Coronavirus from Patients with Pneumonia in China, 2019 Zhu, Na Zhang, Dingyu Wang, Wenling Li, Xingwang Yang, Bo Song, Jingdong Zhao, Xiang Huang, Baoying Shi, Weifeng Lu, Roujian Niu, Peihua Zhan, Faxian Ma, Xuejun Wang, Dayan Xu, Wenbo Wu, Guizhen Gao, George F. Tan, Wenjie N Engl J Med Original Article In December 2019, a cluster of patients with pneumonia of unknown cause was linked to a seafood wholesale market in Wuhan, China. A previously unknown betacoronavirus was discovered through the use of unbiased sequencing in samples from patients with pneumonia. Human airway epithelial cells were used to isolate a novel coronavirus, named 2019-nCoV, which formed a clade within the subgenus sarbecovirus, Orthocoronavirinae subfamily. Different from both MERS-CoV and SARS-CoV, 2019-nCoV is the seventh member of the family of coronaviruses that infect humans. Enhanced surveillance and further investigation are ongoing. (Funded by the National Key Research and Development Program of China and the National Major Project for Control and Prevention of Infectious Disease in China.) Massachusetts Medical Society 2020-02-20 /pmc/articles/PMC7092803/ /pubmed/31978945 http://dx.doi.org/10.1056/NEJMoa2001017 Text en Copyright © 2020 Massachusetts Medical Society. All rights reserved. This article is made available via the PMC Open Access Subset for unrestricted re-use, except commercial resale, and analyses in any form or by any means with acknowledgment of the original source. These permissions are granted for the duration of the Covid-19 pandemic or until revoked in writing. Upon expiration of these permissions, PMC is granted a license to make this article available via PMC and Europe PMC, subject to existing copyright protections.
spellingShingle Original Article
Zhu, Na
Zhang, Dingyu
Wang, Wenling
Li, Xingwang
Yang, Bo
Song, Jingdong
Zhao, Xiang
Huang, Baoying
Shi, Weifeng
Lu, Roujian
Niu, Peihua
Zhan, Faxian
Ma, Xuejun
Wang, Dayan
Xu, Wenbo
Wu, Guizhen
Gao, George F.
Tan, Wenjie
A Novel Coronavirus from Patients with Pneumonia in China, 2019
title A Novel Coronavirus from Patients with Pneumonia in China, 2019
title_full A Novel Coronavirus from Patients with Pneumonia in China, 2019
title_fullStr A Novel Coronavirus from Patients with Pneumonia in China, 2019
title_full_unstemmed A Novel Coronavirus from Patients with Pneumonia in China, 2019
title_short A Novel Coronavirus from Patients with Pneumonia in China, 2019
title_sort novel coronavirus from patients with pneumonia in china, 2019
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092803/
https://www.ncbi.nlm.nih.gov/pubmed/31978945
http://dx.doi.org/10.1056/NEJMoa2001017
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