In vitro inhibition of severe acute respiratory syndrome coronavirus by chloroquine

We report on chloroquine, a 4-amino-quinoline, as an effective inhibitor of the replication of the severe acute respiratory syndrome coronavirus (SARS-CoV) in vitro. Chloroquine is a clinically approved drug effective against malaria. We tested chloroquine phosphate for its antiviral potential again...

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Detalles Bibliográficos
Autores principales: Keyaerts, Els, Vijgen, Leen, Maes, Piet, Neyts, Johan, Ranst, Marc Van
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092815/
https://www.ncbi.nlm.nih.gov/pubmed/15351731
http://dx.doi.org/10.1016/j.bbrc.2004.08.085