Crystal structure of the catalytic domain of Clostridium perfringens neuraminidase in complex with a non-carbohydrate-based inhibitor, 2-(cyclohexylamino)ethanesulfonic acid

Anti-bacterial and anti-viral neuraminidase agents inhibit neuraminidase activity catalyzing the hydrolysis of terminal N-acetylneuraminic acid (Neu5Ac) from glycoconjugates and help to prevent the host pathogenesis that lead to fatal infectious diseases including influenza, bacteremia, sepsis, and...

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Detalles Bibliográficos
Autores principales: Lee, Youngjin, Youn, Hyung-Seop, Lee, Jung-Gyu, An, Jun Yop, Park, Kyoung Ryoung, Kang, Jung Youn, Ryu, Young Bae, Jin, Mi Sun, Park, Ki Hun, Eom, Soo Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092837/
https://www.ncbi.nlm.nih.gov/pubmed/28315686
http://dx.doi.org/10.1016/j.bbrc.2017.03.064

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