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VHL negatively regulates SARS coronavirus replication by modulating nsp16 ubiquitination and stability

Eukaryotic cellular and most viral RNAs carry a 5′-terminal cap structure, a 5′-5′ triphosphate linkage between the 5′ end of the RNA and a guanosine nucleotide (cap-0). SARS coronavirus (SARS-CoV) nonstructural protein nsp16 functions as a methyltransferase, to methylate mRNA cap-0 structure at the...

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Detalles Bibliográficos
Autores principales:	Yu, Xiao, Chen, Shuliang, Hou, Panpan, Wang, Min, Chen, Yu, Guo, Deyin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Inc. 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092858/ https://www.ncbi.nlm.nih.gov/pubmed/25732088 http://dx.doi.org/10.1016/j.bbrc.2015.02.097

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