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Does reduced MHC diversity decrease viability of vertebrate populations?

Loss of genetic variation may render populations more vulnerable to pathogens due to inbreeding depression and depletion of variation in genes responsible for immunity against parasites. Here we review the evidence for the significance of variation in genes of the Major Histocompatibility Complex (M...

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Detalles Bibliográficos
Autores principales: Radwan, Jacek, Biedrzycka, Aleksandra, Babik, Wiesław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092871/
https://www.ncbi.nlm.nih.gov/pubmed/32226082
http://dx.doi.org/10.1016/j.biocon.2009.07.026

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