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Isolation of inhibitory RNA aptamers against severe acute respiratory syndrome (SARS) coronavirus NTPase/Helicase

Recent outbreak of Severe Acute Respiratory Syndrome (SARS) that caused almost 800 victims requires a development of efficient inhibitor against SARS coronavirus (SCV). In this study, RNA aptamers against SCV NTPase/Helicase (nsP10) were isolated from RNA library containing random sequences of 40 nt...

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Detalles Bibliográficos
Autores principales: Jang, Kyoung Jin, Lee, Na-Ra, Yeo, Woon-Seok, Jeong, Yong-Joo, Kim, Dong-Eun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092905/
https://www.ncbi.nlm.nih.gov/pubmed/18082623
http://dx.doi.org/10.1016/j.bbrc.2007.12.020