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Mutational and inhibitive analysis of SARS coronavirus 3C-like protease by fluorescence resonance energy transfer-based assays

The 3C-like protease (3CL(pro)) of severe acute respiratory syndrome coronavirus (SARS-CoV) plays key roles in viral replication and is an attractive target for anti-SARS drug discovery. In this report, a fluorescence resonance energy transfer (FRET)-based method was developed to assess the proteoly...

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Detalles Bibliográficos
Autores principales:	Kuang, Wan-Fen, Chow, Lu-Ping, Wu, Mei-Hua, Hwang, Lih-Hwa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Inc. 2005
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092943/ https://www.ncbi.nlm.nih.gov/pubmed/15883050 http://dx.doi.org/10.1016/j.bbrc.2005.04.072

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