Cargando…

Predicting Skeletal Muscle and Whole-Body Insulin Sensitivity Using NMR-Metabolomic Profiling

PURPOSE: Abnormal lipoprotein and amino acid profiles are associated with insulin resistance and may help to identify this condition. The aim of this study was to create models estimating skeletal muscle and whole-body insulin sensitivity using fasting metabolite profiles and common clinical and lab...

Descripción completa

Detalles Bibliográficos
Autores principales:	Klén, Riku, Honka, Miikka-Juhani, Hannukainen, Jarna C, Huovinen, Ville, Bucci, Marco, Latva-Rasku, Aino, Venäläinen, Mikko S, Kalliokoski, Kari K, Virtanen, Kirsi A, Lautamäki, Riikka, Iozzo, Patricia, Elo, Laura L, Nuutila, Pirjo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Clinical Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093091/ https://www.ncbi.nlm.nih.gov/pubmed/32232183 http://dx.doi.org/10.1210/jendso/bvaa026

Ejemplares similares

Insulin-stimulated glucose uptake in skeletal muscle, adipose tissue and liver: a positron emission tomography study
por: Honka, Miikka-Juhani, et al.
Publicado: (2018)

Effects of Insulin on Brain Glucose Metabolism in Impaired Glucose Tolerance
por: Hirvonen, Jussi, et al.
Publicado: (2011)

Brain substrate metabolism and ß‐cell function in humans: A positron emission tomography study
por: Rebelos, Eleni, et al.
Publicado: (2020)

The Obesity Risk SNP (rs17782313) near the MC4R Gene Is Not Associated with Brain Glucose Uptake during Insulin Clamp—A Study in Finns
por: Rebelos, Eleni, et al.
Publicado: (2021)

Insulin Resistance Is Associated With Enhanced Brain Glucose Uptake During Euglycemic Hyperinsulinemia: A Large-Scale PET Cohort
por: Rebelos, Eleni, et al.
Publicado: (2021)

Brain glucose uptake is associated with endogenous glucose production in obese patients before and after bariatric surgery and predicts metabolic outcome at follow‐up
por: Rebelos, Eleni, et al.
Publicado: (2018)

Reversibility of myocardial metabolism and remodelling in morbidly obese patients 6 months after bariatric surgery
por: Hannukainen, Jarna C., et al.
Publicado: (2018)

Circulating Docosahexaenoic Acid Associates with Insulin-Dependent Skeletal Muscle and Whole Body Glucose Uptake in Older Women Born from Normal Weight Mothers
por: Badeau, Robert M., et al.
Publicado: (2017)

Brain insulin sensitivity is linked to body fat distribution—the positron emission tomography perspective
por: Rebelos, Eleni, et al.
Publicado: (2020)

Stable Iterative Variable Selection
por: Mahmoudian, Mehrad, et al.
Publicado: (2021)

Pleiotropic Effects of Secretin: A Potential Drug Candidate in the Treatment of Obesity?
por: Laurila, Sanna, et al.
Publicado: (2021)

Hepatic Positron Emission Tomography: Applications in Metabolism, Haemodynamics and Cancer
por: Honka, Miikka-Juhani, et al.
Publicado: (2022)

Exercise Training Modulates Gut Microbiota Profile and Improves Endotoxemia
por: MOTIANI, KUMAIL K., et al.
Publicado: (2020)

Exercise training decreases pancreatic fat content and improves beta cell function regardless of baseline glucose tolerance: a randomised controlled trial
por: Heiskanen, Marja A., et al.
Publicado: (2018)

Obesity risk is associated with brain glucose uptake and insulin resistance
por: Pekkarinen, Laura, et al.
Publicado: (2022)

Novel effects of the gastrointestinal hormone secretin on cardiac metabolism and renal function
por: Laurila, Sanna, et al.
Publicado: (2022)

Brain free fatty acid uptake is elevated in morbid obesity, and is irreversible 6 months after bariatric surgery: A positron emission tomography study
por: Rebelos, Eleni, et al.
Publicado: (2020)

Effects of DAPAgliflozin on CARDiac substrate uptake, myocardial efficiency, and myocardial contractile work in type 2 diabetes patients—a description of the DAPACARD study
por: Åkerblom, Axel, et al.
Publicado: (2019)

Human Bone Marrow Adipose Tissue is a Metabolically Active and Insulin-Sensitive Distinct Fat Depot
por: Pham, Tam T, et al.
Publicado: (2020)

Exercise training improves adipose tissue metabolism and vasculature regardless of baseline glucose tolerance and sex
por: Honkala, Sanna Maria, et al.
Publicado: (2020)

Femoral Bone Marrow Insulin Sensitivity Is Increased by Resistance Training in Elderly Female Offspring of Overweight and Obese Mothers
por: Huovinen, Ville, et al.
Publicado: (2016)

Bone Marrow Metabolism Is Impaired in Insulin Resistance and Improves After Exercise Training
por: Ojala, Ronja, et al.
Publicado: (2020)

Finnish-specific AKT2 gene variant leads to impaired insulin signalling in myotubes
por: Mäkinen, Selina, et al.
Publicado: (2022)

Decreased insulin‐stimulated brown adipose tissue glucose uptake after short‐term exercise training in healthy middle‐aged men
por: Motiani, Piryanka, et al.
Publicado: (2017)

Intramyocellular lipid accumulation after sprint interval and moderate‐intensity continuous training in healthy and diabetic subjects
por: Sjöros, Tanja, et al.
Publicado: (2019)

Sprint interval training decreases left-ventricular glucose uptake compared to moderate-intensity continuous training in subjects with type 2 diabetes or prediabetes
por: Heiskanen, Marja A., et al.
Publicado: (2017)

Exercise Training Reduces Intrathoracic Fat Regardless of Defective Glucose Tolerance
por: HONKALA, SANNA M., et al.
Publicado: (2017)

Dorsal Striatum and Its Limbic Connectivity Mediate Abnormal Anticipatory Reward Processing in Obesity
por: Nummenmaa, Lauri, et al.
Publicado: (2012)

Obesity-associated intestinal insulin resistance is ameliorated after bariatric surgery
por: Mäkinen, Jaakko, et al.
Publicado: (2015)

Two weeks of moderate-intensity continuous training, but not high-intensity interval training, increases insulin-stimulated intestinal glucose uptake
por: Motiani, Kumail K., et al.
Publicado: (2017)

Circulating neurofilament is linked with morbid obesity, renal function, and brain density
por: Rebelos, Eleni, et al.
Publicado: (2022)

Resistance Training Increases White Matter Density in Frail Elderly Women
por: Bucci, Marco, et al.
Publicado: (2023)

Exercise intensity regulates cytokine and klotho responses in men
por: Middelbeek, Roeland J. W., et al.
Publicado: (2021)

Partial restoration of normal intestinal microbiota in morbidly obese women six months after bariatric surgery
por: Koffert, Jukka, et al.
Publicado: (2020)

Posterior approach, fracture diagnosis, and american society of anesthesiology class iii–iv are associated with increased risk of revision for dislocation after total hip arthroplasty: An analysis of 33,337 operations from the finnish arthroplasty register
por: Panula, Valtteri J., et al.
Publicado: (2020)

Different Predictors of Right and Left Ventricular Metabolism in Healthy Middle-Aged Men
por: Heiskanen, Marja A., et al.
Publicado: (2015)

Elevated Glucose Oxidation, Reduced Insulin Secretion, and a Fatty Heart May Be Protective Adaptions in Ischemic CAD
por: Hannukainen, J. C., et al.
Publicado: (2016)

Obesity-associated Blunted Subcutaneous Adipose Tissue Blood Flow After Meal Improves After Bariatric Surgery
por: Saari, Teemu, et al.
Publicado: (2022)

Weight Loss After Bariatric Surgery Reverses Insulin-Induced Increases in Brain Glucose Metabolism of the Morbidly Obese
por: Tuulari, Jetro J., et al.
Publicado: (2013)

Erratum. Weight Loss After Bariatric Surgery Reverses Insulin-Induced Increases in Brain Glucose Metabolism of the Morbidly Obese. Diabetes 2013;62:2747–2751
por: Tuulari, Jetro J., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_nkdrjpqsv5jjd3garn3c83o0ro