Structural and Biomolecular Analyses of Borrelia burgdorferi BmpD Reveal a Substrate-Binding Protein of an ABC-Type Nucleoside Transporter Family

Borrelia burgdorferi sensu lato, the causative agent of tick-borne Lyme borreliosis (LB), has a limited metabolic capacity and needs to acquire nutrients, such as amino acids, fatty acids, and nucleic acids, from the host environment. Using X-ray crystallography, liquid chromatography-mass spectrome...

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Detalles Bibliográficos
Autores principales: Cuellar, Julia, Åstrand, Mia, Elovaara, Heli, Pietikäinen, Annukka, Sirén, Saija, Liljeblad, Arto, Guédez, Gabriela, Salminen, Tiina A., Hytönen, Jukka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093131/
https://www.ncbi.nlm.nih.gov/pubmed/31988175
http://dx.doi.org/10.1128/IAI.00962-19

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