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Genetic variants in RET, ARHGEF3 and CTNNAL1, and relevant interaction networks, contribute to the risk of Hirschsprung disease

Hirschsprung disease (HSCR), the most common enteric neuropathy, stands as a model for complex genetic disorders. It has recently been demonstrated that both ARHGEF3 and CTNNAL1 map to the RET-dependent HSCR susceptibility loci. We therefore sought to explore whether genetic variants within RET, ARH...

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Detalles Bibliográficos
Autores principales:	Wang, Yang, Jiang, Qian, Cai, Hao, Xu, Ze, Wu, Wenjie, Gu, Beilin, Li, Long, Cai, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093166/ https://www.ncbi.nlm.nih.gov/pubmed/32139661 http://dx.doi.org/10.18632/aging.102891

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