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SIRT3 inhibits cardiac hypertrophy by regulating PARP-1 activity

Sirtuin 3 (SIRT3) is a type III histone deacetylase that inhibits cardiac hypertrophy. It is mainly localized in the mitochondria and is thus implicated in mitochondrial metabolism. Recent studies have shown that SIRT3 can also accumulate in the nuclear under stressed conditions, and participated in...

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Detalles Bibliográficos
Autores principales: Feng, Xiaojun, Wang, Yanan, Chen, Wenxu, Xu, Suowen, Li, Lingli, Geng, Yadi, Shen, Aizong, Gao, Hui, Zhang, Lei, Liu, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093179/
https://www.ncbi.nlm.nih.gov/pubmed/32139662
http://dx.doi.org/10.18632/aging.102862