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SIRT3 inhibits cardiac hypertrophy by regulating PARP-1 activity
Sirtuin 3 (SIRT3) is a type III histone deacetylase that inhibits cardiac hypertrophy. It is mainly localized in the mitochondria and is thus implicated in mitochondrial metabolism. Recent studies have shown that SIRT3 can also accumulate in the nuclear under stressed conditions, and participated in...
Autores principales: | Feng, Xiaojun, Wang, Yanan, Chen, Wenxu, Xu, Suowen, Li, Lingli, Geng, Yadi, Shen, Aizong, Gao, Hui, Zhang, Lei, Liu, Sheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093179/ https://www.ncbi.nlm.nih.gov/pubmed/32139662 http://dx.doi.org/10.18632/aging.102862 |
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