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Cholesterol uptake and efflux are impaired in human trophoblast cells from pregnancies with maternal supraphysiological hypercholesterolemia

Maternal physiological (MPH) or supraphysiological hypercholesterolaemia (MSPH) occurs during pregnancy. Cholesterol trafficking from maternal to foetal circulation requires the uptake of maternal LDL and HDL by syncytiotrophoblast and cholesterol efflux from this multinucleated tissue to ApoA-I and...

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Detalles Bibliográficos
Autores principales:	Fuenzalida, Bárbara, Cantin, Claudette, Kallol, Sampada, Carvajal, Lorena, Pastén, Valentina, Contreras-Duarte, Susana, Albrecht, Christiane, Gutierrez, Jaime, Leiva, Andrea
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093446/ https://www.ncbi.nlm.nih.gov/pubmed/32210256 http://dx.doi.org/10.1038/s41598-020-61629-4

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