Cargando…
Teriparatide relieves ovariectomy-induced hyperalgesia in rats, suggesting the involvement of functional regulation in primary sensory neurons by PTH-mediated signaling
Clinical studies have reported that teriparatide (TPTD), a human parathyroid hormone analog, reduces back pain in osteoporotic patients. However, the mechanistic insights of this pharmacological action remain elusive. This study investigated the antinociceptive effect of TPTD mainly on primary senso...
Autores principales: | Tanaka, Tomoya, Takao-Kawabata, Ryoko, Takakura, Aya, Shimazu, Yukari, Nakatsugawa, Momoko, Ito, Akitoshi, Lee, Ji-Won, Kawasaki, Koh, Iimura, Tadahiro |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093455/ https://www.ncbi.nlm.nih.gov/pubmed/32210273 http://dx.doi.org/10.1038/s41598-020-62045-4 |
Ejemplares similares
-
Administration frequency as well as dosage of PTH are associated with development of cortical porosity in ovariectomized rats
por: Takakura, Aya, et al.
Publicado: (2017) -
Acute development of cortical porosity and endosteal naïve bone formation from the daily but not weekly short-term administration of PTH in rabbit
por: Yamane, Hiroshi, et al.
Publicado: (2017) -
A quantitative analysis of bone lamellarity and bone collagen linearity induced by distinct dosing and frequencies of teriparatide administration in ovariectomized rats and monkeys
por: Sato, Takanori, et al.
Publicado: (2021) -
Expansion of the osteocytic lacunar-canalicular system involved in pharmacological action of PTH revealed by AI-driven fluorescence morphometry in female rabbits
por: Takakura, Aya, et al.
Publicado: (2022) -
Early Effects of Single and Low-Frequency Repeated Administration of Teriparatide, hPTH(1-34), on Bone Formation and Resorption in Ovariectomized Rats
por: Isogai, Yukihiro, et al.
Publicado: (2015)