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Lactate Beyond a Waste Metabolite: Metabolic Affairs and Signaling in Malignancy
To sustain their high proliferation rates, most cancer cells rely on glycolytic metabolism, with production of lactic acid. For many years, lactate was seen as a metabolic waste of glycolytic metabolism; however, recent evidence has revealed new roles of lactate in the tumor microenvironment, either...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093491/ https://www.ncbi.nlm.nih.gov/pubmed/32257942 http://dx.doi.org/10.3389/fonc.2020.00231 |