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Janus effect of glucocorticoids on differentiation of muscle fibro/adipogenic progenitors
Muscle resident fibro-adipogenic progenitors (FAPs), support muscle regeneration by releasing cytokines that stimulate the differentiation of myogenic stem cells. However, in non-physiological contexts (myopathies, atrophy, aging) FAPs cause fibrotic and fat infiltrations that impair muscle function...
Autores principales: | Cerquone Perpetuini, Andrea, Giuliani, Giulio, Reggio, Alessio, Cerretani, Mauro, Santoriello, Marisabella, Stefanelli, Roberta, Palma, Alessandro, Vumbaca, Simone, Harper, Steven, Castagnoli, Luisa, Bresciani, Alberto, Cesareni, Gianni |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093513/ https://www.ncbi.nlm.nih.gov/pubmed/32210313 http://dx.doi.org/10.1038/s41598-020-62194-6 |
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