Cargando…
Rank orders of mammalian pathogenicity-related PB2 mutations of avian influenza A viruses
The PB2 gene is one of the key determinants for the mammalian adaptation of avian influenza A viruses (IAVs). Although mammalian pathogenicity-related mutations (MPMs) in PB2 genes were identified in different genetic backgrounds of avian IAVs, the relative effects of single or multiple mutations on...
Autores principales: | Lee, Chung-Young, An, Se-Hee, Choi, Jun-Gu, Lee, Youn-Jeong, Kim, Jae-Hong, Kwon, Hyuk-Joon |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093554/ https://www.ncbi.nlm.nih.gov/pubmed/32210274 http://dx.doi.org/10.1038/s41598-020-62036-5 |
Ejemplares similares
-
Prerequisites for the acquisition of mammalian pathogenicity by influenza A virus with a prototypic avian PB2 gene
por: Lee, Chung-Young, et al.
Publicado: (2017) -
Acquisition of Innate Inhibitor Resistance and Mammalian Pathogenicity During Egg Adaptation by the H9N2 Avian Influenza Virus
por: Lee, Chung-Young, et al.
Publicado: (2018) -
Novel Mutations Evading Avian Immunity around the Receptor Binding Site of the Clade 2.3.2.1c Hemagglutinin Gene Reduce Viral Thermostability and Mammalian Pathogenicity
por: An, Se-Hee, et al.
Publicado: (2019) -
Optimized clade 2.3.2.1c H5N1 recombinant-vaccine strains against highly pathogenic avian influenza
por: Jang, Jin-Wook, et al.
Publicado: (2017) -
Selection of an Optimal Recombinant Egyptian H9N2 Avian Influenza Vaccine Strain for Poultry with High Antigenicity and Safety
por: An, Se-Hee, et al.
Publicado: (2022)