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Model-Based Simulation of Maintenance Therapy of Childhood Acute Lymphoblastic Leukemia

Acute lymphoblastic leukemia is the most common malignancy in childhood. Successful treatment requires initial high-intensity chemotherapy, followed by low-intensity oral maintenance therapy with oral 6-mercaptopurine (6MP) and methotrexate (MTX) until 2–3 years after disease onset. However, intra-...

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Detalles Bibliográficos
Autores principales:	Jost, Felix, Zierk, Jakob, Le, Thuy T. T., Raupach, Thomas, Rauh, Manfred, Suttorp, Meinolf, Stanulla, Martin, Metzler, Markus, Sager, Sebastian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093595/ https://www.ncbi.nlm.nih.gov/pubmed/32256384 http://dx.doi.org/10.3389/fphys.2020.00217

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