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Single-Molecule Force Spectroscopy on the N2A Element of Titin: Effects of Phosphorylation and CARP
Titin is a large filamentous protein that forms a sarcomeric myofilament with a molecular spring region that develops force in stretched sarcomeres. The molecular spring has a complex make-up that includes the N2A element. This element largely consists of a 104-residue unique sequence (N2A-Us) flank...
Autores principales: | Lanzicher, Thomas, Zhou, Tiankun, Saripalli, Chandra, Keschrumrus, Vic, Smith III, John E., Mayans, Olga, Sbaizero, Orfeo, Granzier, Henk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093598/ https://www.ncbi.nlm.nih.gov/pubmed/32256378 http://dx.doi.org/10.3389/fphys.2020.00173 |
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