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Value of initial chest radiographs for predicting clinical outcomes in patients with severe acute respiratory syndrome
PURPOSE: To determine whether the initial chest radiograph is helpful in predicting the clinical outcome of patients with severe acute respiratory syndrome (SARS). METHODS: Of 343 patients who met the World Health Organization’s case definition of probable SARS and who had been admitted to a regiona...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093886/ https://www.ncbi.nlm.nih.gov/pubmed/15308434 http://dx.doi.org/10.1016/j.amjmed.2004.03.020 |
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author | Chau, Tai-nin Lee, Po-oi Choi, Kin-wing Lee, Chiu-man Ma, Ka-fai Tsang, Tak-yin Tso, Yuk-keung Chiu, Ming-chee Tong, Wing-lok Yu, Wai-cho Lai, Sik-to |
author_facet | Chau, Tai-nin Lee, Po-oi Choi, Kin-wing Lee, Chiu-man Ma, Ka-fai Tsang, Tak-yin Tso, Yuk-keung Chiu, Ming-chee Tong, Wing-lok Yu, Wai-cho Lai, Sik-to |
author_sort | Chau, Tai-nin |
collection | PubMed |
description | PURPOSE: To determine whether the initial chest radiograph is helpful in predicting the clinical outcome of patients with severe acute respiratory syndrome (SARS). METHODS: Of 343 patients who met the World Health Organization’s case definition of probable SARS and who had been admitted to a regional hospital in Hong Kong, 201 patients had laboratory evidence of SARS coronavirus infection. The initial frontal chest radiographs of these 201 patients were assessed in a blinded fashion by 3 radiologists; individual findings were accepted if at least 2 of the radiologists concurred. Independent predictors of an adverse outcome, defined as the need for assisted ventilation, death, or both, were identified by multivariate analysis. RESULTS: Bilateral disease and involvement of more than two zones on the initial chest radiograph were associated with a higher risk of liver impairment and poor clinical outcome. Forty-two patients (21%) developed an adverse outcome. Multivariate analysis showed that lung involvement of more than two zones (odds ratio [OR] = 7.0; 95% confidence interval [CI]: 2.7 to 17.9), older age (OR for each decade of life = 1.5; 95% CI: 1.1 to 2.0), and shortness of breath on admission (OR = 2.8; 95% CI: 1.1 to 7.4) were independent predictors of an adverse outcome. CONCLUSION: Frontal chest radiographs on presentation may have prognostic value in patients with SARS. |
format | Online Article Text |
id | pubmed-7093886 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2004 |
publisher | Elsevier Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-70938862020-03-25 Value of initial chest radiographs for predicting clinical outcomes in patients with severe acute respiratory syndrome Chau, Tai-nin Lee, Po-oi Choi, Kin-wing Lee, Chiu-man Ma, Ka-fai Tsang, Tak-yin Tso, Yuk-keung Chiu, Ming-chee Tong, Wing-lok Yu, Wai-cho Lai, Sik-to Am J Med Article PURPOSE: To determine whether the initial chest radiograph is helpful in predicting the clinical outcome of patients with severe acute respiratory syndrome (SARS). METHODS: Of 343 patients who met the World Health Organization’s case definition of probable SARS and who had been admitted to a regional hospital in Hong Kong, 201 patients had laboratory evidence of SARS coronavirus infection. The initial frontal chest radiographs of these 201 patients were assessed in a blinded fashion by 3 radiologists; individual findings were accepted if at least 2 of the radiologists concurred. Independent predictors of an adverse outcome, defined as the need for assisted ventilation, death, or both, were identified by multivariate analysis. RESULTS: Bilateral disease and involvement of more than two zones on the initial chest radiograph were associated with a higher risk of liver impairment and poor clinical outcome. Forty-two patients (21%) developed an adverse outcome. Multivariate analysis showed that lung involvement of more than two zones (odds ratio [OR] = 7.0; 95% confidence interval [CI]: 2.7 to 17.9), older age (OR for each decade of life = 1.5; 95% CI: 1.1 to 2.0), and shortness of breath on admission (OR = 2.8; 95% CI: 1.1 to 7.4) were independent predictors of an adverse outcome. CONCLUSION: Frontal chest radiographs on presentation may have prognostic value in patients with SARS. Elsevier Inc. 2004-08-15 2004-08-10 /pmc/articles/PMC7093886/ /pubmed/15308434 http://dx.doi.org/10.1016/j.amjmed.2004.03.020 Text en Copyright © 2004 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Chau, Tai-nin Lee, Po-oi Choi, Kin-wing Lee, Chiu-man Ma, Ka-fai Tsang, Tak-yin Tso, Yuk-keung Chiu, Ming-chee Tong, Wing-lok Yu, Wai-cho Lai, Sik-to Value of initial chest radiographs for predicting clinical outcomes in patients with severe acute respiratory syndrome |
title | Value of initial chest radiographs for predicting clinical outcomes in patients with severe acute respiratory syndrome |
title_full | Value of initial chest radiographs for predicting clinical outcomes in patients with severe acute respiratory syndrome |
title_fullStr | Value of initial chest radiographs for predicting clinical outcomes in patients with severe acute respiratory syndrome |
title_full_unstemmed | Value of initial chest radiographs for predicting clinical outcomes in patients with severe acute respiratory syndrome |
title_short | Value of initial chest radiographs for predicting clinical outcomes in patients with severe acute respiratory syndrome |
title_sort | value of initial chest radiographs for predicting clinical outcomes in patients with severe acute respiratory syndrome |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093886/ https://www.ncbi.nlm.nih.gov/pubmed/15308434 http://dx.doi.org/10.1016/j.amjmed.2004.03.020 |
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