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Knocking Down TcNTPDase-1 Gene Reduces in vitro Infectivity of Trypanosoma cruzi

Ecto-Nucleoside Triphosphate Diphosphohydrolases are enzymes that hydrolyze tri- and/or diphosphate nucleosides. Evidences pointed out to their participation in Trypanosoma cruzi virulence, infectivity, and purine acquisition. In this study, recombinant T. cruzi knocking out or overexpressing the Tc...

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Detalles Bibliográficos
Autores principales: Silva-Gomes, Natália Lins, Rampazzo, Rita de Cássia Pontello, Moreira, Claudia Maria do Nascimento, Porcino, Gabriane Nascimento, dos Santos, Cyndia Mara Bezerra, Krieger, Marco Aurélio, Vasconcelos, Eveline Gomes, Fragoso, Stenio Perdigão, Moreira, Otacilio C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094052/
https://www.ncbi.nlm.nih.gov/pubmed/32256481
http://dx.doi.org/10.3389/fmicb.2020.00434

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