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Knocking Down TcNTPDase-1 Gene Reduces in vitro Infectivity of Trypanosoma cruzi
Ecto-Nucleoside Triphosphate Diphosphohydrolases are enzymes that hydrolyze tri- and/or diphosphate nucleosides. Evidences pointed out to their participation in Trypanosoma cruzi virulence, infectivity, and purine acquisition. In this study, recombinant T. cruzi knocking out or overexpressing the Tc...
Autores principales: | Silva-Gomes, Natália Lins, Rampazzo, Rita de Cássia Pontello, Moreira, Claudia Maria do Nascimento, Porcino, Gabriane Nascimento, dos Santos, Cyndia Mara Bezerra, Krieger, Marco Aurélio, Vasconcelos, Eveline Gomes, Fragoso, Stenio Perdigão, Moreira, Otacilio C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094052/ https://www.ncbi.nlm.nih.gov/pubmed/32256481 http://dx.doi.org/10.3389/fmicb.2020.00434 |
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