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Molecular modeling and chemical modification for finding peptide inhibitor against severe acute respiratory syndrome coronavirus main proteinase
Severe acute respiratory syndrome (SARS) is a respiratory disease caused by a newly found virus, called SARS coronavirus. In this study, the cleavage mechanism of the SARS coronavirus main proteinase (M(pro) or 3CL(pro)) on the octapeptide NH(2)-AVLQ ↓ SGFR-COOH was investigated using molecular mech...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Inc.
2005
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094278/ https://www.ncbi.nlm.nih.gov/pubmed/15691506 http://dx.doi.org/10.1016/j.ab.2004.10.003 |