Cargando…

Enzymatic activity of the SARS coronavirus main proteinase dimer

The enzymatic activity of the SARS coronavirus main proteinase dimer was characterized by a sensitive, quantitative assay. The new, fluorogenic substrate, (Ala‐Arg‐Leu‐Gln‐NH)(2)‐Rhodamine, contained a severe acute respiratory syndrome coronavirus (SARS CoV) main proteinase consensus cleavage sequen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Graziano, Vito, McGrath, William J., DeGruccio, Ann Marie, Dunn, John J., Mangel, Walter F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2006
Materias:	Short Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094300/ https://www.ncbi.nlm.nih.gov/pubmed/16647061 http://dx.doi.org/10.1016/j.febslet.2006.04.004

Ejemplares similares

Structure of the SARS coronavirus main proteinase as an active C(2) crystallographic dimer
por: Xu, Ting, et al.
Publicado: (2005)

Structure and Dynamics of Sars Coronavirus Main Proteinase (M(PRO))
por: Hilgenfeld, Rolf, et al.
Publicado: (2006)

Generation of predictive pharmacophore model for SARS-coronavirus main proteinase
por: Zhang, Xue Wu, et al.
Publicado: (2005)

Homology models of main proteinase from coronavirus associated with SARS
por: Liu, Hsuan-Liang, et al.
Publicado: (2005)

SARS coronavirus main proteinase 3.4.22.69
por: Schomburg, Dietmar, et al.
Publicado: (2013)

Synthesis and activity of an octapeptide inhibitor designed for SARS coronavirus main proteinase
por: Gan, Yi-Ru, et al.
Publicado: (2006)

High-Throughput Screening Identifies Inhibitors of the SARS Coronavirus Main Proteinase
por: Blanchard, Jan E., et al.
Publicado: (2004)

A Structural View of the Inactivation of the SARS Coronavirus Main Proteinase by Benzotriazole Esters
por: Verschueren, Koen H.G., et al.
Publicado: (2008)

Coronavirus main proteinase: target for antiviral drug therapy
por: Anand, Kanchan, et al.
Publicado: (2005)

Prediction of potential inhibitors of the dimeric SARS-CoV2 main proteinase through the MM/GBSA approach
por: Bello, Martiniano
Publicado: (2020)

The N-terminal octapeptide acts as a dimerization inhibitor of SARS coronavirus 3C-like proteinase()
por: Wei, Ping, et al.
Publicado: (2006)

Binding mechanism of coronavirus main proteinase with ligands and its implication to drug design against SARS()
por: Chou, Kuo-Chen, et al.
Publicado: (2003)

Molecular sled is an eleven-amino acid vehicle facilitating biochemical interactions via sliding components along DNA
por: Mangel, Walter F., et al.
Publicado: (2016)

Identifying inhibitors of the SARS coronavirus proteinase
por: Jenwitheesuk, Ekachai, et al.
Publicado: (2003)

Exploring the binding mechanism of the main proteinase in SARS-associated coronavirus and its implication to anti-SARS drug design
por: Zhang, Xue Wu, et al.
Publicado: (2004)

Only One Protomer Is Active in the Dimer of SARS 3C-like Proteinase
por: Chen, Hao, et al.
Publicado: (2006)

Quality of MIS vs Open Joint Preparations of the Foot and Ankle
por: Zhao, John Z., et al.
Publicado: (2022)

IA3, A Yeast Proteinase A Inhibitor, Is Intrinsically Unstructured in Solution
por: Green, Terry, et al.
Publicado: (2002)

Mutation of Glu-166 Blocks the Substrate-Induced Dimerization of SARS Coronavirus Main Protease
por: Cheng, Shu-Chun, et al.
Publicado: (2010)

The substrate specificity of SARS coronavirus 3C-like proteinase
por: Fan, Keqiang, et al.
Publicado: (2005)

Structure of coronavirus main proteinase reveals combination of a chymotrypsin fold with an extra α-helical domain
por: Anand, Kanchan, et al.
Publicado: (2002)

Expression, purification, and in vitro activity of an arterivirus main proteinase
por: van Aken, Danny, et al.
Publicado: (2006)

In Silico Drug Repurposing for SARS-CoV-2 Main Proteinase and Spike Proteins
por: Maffucci, Irene, et al.
Publicado: (2020)

Old drugs as lead compounds for a new disease? Binding analysis of SARS coronavirus main proteinase with HIV, psychotic and parasite drugs
por: Zhang, Xue Wu, et al.
Publicado: (2004)

pH-dependent Conformational Flexibility of the SARS-CoV Main Proteinase (M(pro)) Dimer: Molecular Dynamics Simulations and Multiple X-ray Structure Analyses
por: Tan, Jinzhi, et al.
Publicado: (2005)

Coronavirus Picornain-like Cysteine Proteinase
por: Stobart, Christopher C., et al.
Publicado: (2013)

Discovery of juglone and its derivatives as potent SARS-CoV-2 main proteinase inhibitors
por: Cui, Jiahua, et al.
Publicado: (2021)

The dimer interface of the SARS coronavirus nucleocapsid protein adapts a porcine respiratory and reproductive syndrome virus‐like structure
por: Chang, Chung-ke, et al.
Publicado: (2005)

The interaction between severe acute respiratory syndrome coronavirus 3C-like proteinase and a dimeric inhibitor by capillary electrophoresis
por: Ding, Li, et al.
Publicado: (2005)

Individual and common inhibitors of coronavirus and picornavirus main proteases
por: Kuo, Chih-Jung, et al.
Publicado: (2009)

Molecular modeling and chemical modification for finding peptide inhibitor against severe acute respiratory syndrome coronavirus main proteinase
por: Du, Qishi, et al.
Publicado: (2005)

Proteinase K treatment in absence of RNA isolation classical procedures is a quick and cheaper alternative for SARS-CoV-2 molecular detection
por: Mallmann, L., et al.
Publicado: (2021)

Effect of pH on stability of dimer structure of the main protease of coronavirus-2
por: Boonamnaj, Panisak, et al.
Publicado: (2022)

Erratum to “Binding mechanism of coronavirus main proteinase with ligands and its implication to drug design against SARS” [Biochem. Biophys. Res. Commun. 308 (2003) 148–151]
por: Chou, Kuo-Chen, et al.
Publicado: (2003)

Coronavirus 3CL(pro )proteinase cleavage sites: Possible relevance to SARS virus pathology
por: Kiemer, Lars, et al.
Publicado: (2004)

Maturation Mechanism of Severe Acute Respiratory Syndrome (SARS) Coronavirus 3C-like Proteinase
por: Li, Chunmei, et al.
Publicado: (2010)

Critical Assessment of the Important Residues Involved in the Dimerization and Catalysis of MERS Coronavirus Main Protease
por: Ho, Bo-Lin, et al.
Publicado: (2015)

Computational fragment screening of dimeric SARS-CoV-2 main protease
por: Reid, Rashad L., et al.
Publicado: (2023)

Channel catfish, Ictalurus punctatus, cysteine proteinases: Cloning, characterisation and expression of cathepsin H and L
por: Yeh, Hung-Yueh, et al.
Publicado: (2009)

Quaternary Structure of the SARS Coronavirus Main Protease
por: Chang, Gu-Gang
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_2nh74q121fitsk0i0i5v4r2t7h