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Comparison of the efficiency of antibody selection from semi-synthetic scFv and non-immune Fab phage display libraries against protein targets for rapid development of diagnostic immunoassays

Rapid development of diagnostic immunoassays against novel emerging or genetically modified pathogens in an emergency situation is dependent on the timely isolation of specific antibodies. Non-immune antibody phage display libraries are an efficient in vitro method for selecting monoclonal antibodie...

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Detalles Bibliográficos
Autores principales: Chan, Conrad E.Z., Chan, Annie H.Y., Lim, Angeline P.C., Hanson, Brendon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094349/
https://www.ncbi.nlm.nih.gov/pubmed/21856306
http://dx.doi.org/10.1016/j.jim.2011.08.005