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X-ray Structures of the Post-fusion 6-Helix Bundle of the Human Syncytins and their Functional Implications

The retroviral envelope-derived proteins syncytin-1 and syncytin-2 (syn1 and syn2) drive placentation in humans by forming a syncytiotophoblast, a structure allowing for an exchange interface between maternal and fetal blood during pregnancy. Despite their essential role, little is known about the m...

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Detalles Bibliográficos
Autores principales: Ruigrok, Katinka, Vaney, Marie-Christine, Buchrieser, Julian, Baquero, Eduard, Hellert, Jan, Baron, Bruno, England, Patrick, Schwartz, Olivier, Rey, Felix A., Backovic, Marija
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Ltd. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094397/
https://www.ncbi.nlm.nih.gov/pubmed/31711961
http://dx.doi.org/10.1016/j.jmb.2019.10.020

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