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X-ray Structures of the Post-fusion 6-Helix Bundle of the Human Syncytins and their Functional Implications
The retroviral envelope-derived proteins syncytin-1 and syncytin-2 (syn1 and syn2) drive placentation in humans by forming a syncytiotophoblast, a structure allowing for an exchange interface between maternal and fetal blood during pregnancy. Despite their essential role, little is known about the m...
Autores principales: | Ruigrok, Katinka, Vaney, Marie-Christine, Buchrieser, Julian, Baquero, Eduard, Hellert, Jan, Baron, Bruno, England, Patrick, Schwartz, Olivier, Rey, Felix A., Backovic, Marija |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Author(s). Published by Elsevier Ltd.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094397/ https://www.ncbi.nlm.nih.gov/pubmed/31711961 http://dx.doi.org/10.1016/j.jmb.2019.10.020 |
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