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Correlation between dissociation and catalysis of SARS-CoV main protease

The dimeric interface of severe acute respiratory syndrome coronavirus main protease is a potential target for the anti-SARS drug development. We have generated C-terminal truncated mutants by serial truncations. The quaternary structure of the enzyme was analyzed using both sedimentation velocity a...

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Detalles Bibliográficos
Autores principales:	Lin, Pei-Ying, Chou, Chi-Yuan, Chang, Hui-Chuan, Hsu, Wen-Chi, Chang, Gu-Gang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Inc. 2008
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094404/ https://www.ncbi.nlm.nih.gov/pubmed/18275836 http://dx.doi.org/10.1016/j.abb.2008.01.023

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