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Glycyrrhizic acid attenuates growth of Leishmania donovani by depleting ergosterol levels
In the present study, glycyrrhizic acid (GA) the main component of Glycyrrhiza glabra was evaluated for its efficacy as antileishmanial agent and its mode of action explored. GA inhibits promastigotes and intracellular amastigotes in a dose dependent manner at an IC(50) value of 34 ± 3.0 μM and 20 ±...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Inc.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094550/ https://www.ncbi.nlm.nih.gov/pubmed/28242356 http://dx.doi.org/10.1016/j.exppara.2017.02.015 |