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Quantitative comparison of the efficiency of antibodies against S1 and S2 subunit of SARS coronavirus spike protein in virus neutralization and blocking of receptor binding: Implications for the functional roles of S2 subunit

Neutralizing effects of antibodies targeting the C‐terminal stalk (S2) subunit of the spike protein of severe acute respiratory syndrome coronavirus have previously been reported, although its mechanism remained elusive. In this study, high titered mouse antisera against the N‐terminal globular (S1)...

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Detalles Bibliográficos
Autores principales: Zeng, Fanya, Hon, Chung Chau, Yip, Chi Wai, Law, Ka Man, Yeung, Yin Shan, Chan, Kwok Hung, Malik Peiris, Joseph S., Leung, Frederick Chi Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094555/
https://www.ncbi.nlm.nih.gov/pubmed/16989815
http://dx.doi.org/10.1016/j.febslet.2006.08.085

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