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Quantitative comparison of the efficiency of antibodies against S1 and S2 subunit of SARS coronavirus spike protein in virus neutralization and blocking of receptor binding: Implications for the functional roles of S2 subunit
Neutralizing effects of antibodies targeting the C‐terminal stalk (S2) subunit of the spike protein of severe acute respiratory syndrome coronavirus have previously been reported, although its mechanism remained elusive. In this study, high titered mouse antisera against the N‐terminal globular (S1)...
Autores principales: | Zeng, Fanya, Hon, Chung Chau, Yip, Chi Wai, Law, Ka Man, Yeung, Yin Shan, Chan, Kwok Hung, Malik Peiris, Joseph S., Leung, Frederick Chi Ching |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094555/ https://www.ncbi.nlm.nih.gov/pubmed/16989815 http://dx.doi.org/10.1016/j.febslet.2006.08.085 |
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