Cargando…

Características de las infecciones respiratorias agudas causadas por los coronavirus OC43, NL63 y 229E

BACKGROUND AND OBJECTIVES: Acute respiratory infection is a very common condition in the general population. The majority of these infections are due to viruses. This study attempted to determine the clinical and epidemiological characteristics of adult patients with respiratory infection by the cor...

Descripción completa

Detalles Bibliográficos
Autores principales: Reina, J., López-Causapé, C., Rojo-Molinero, E., Rubio, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier España, S.L.U. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094643/
https://www.ncbi.nlm.nih.gov/pubmed/34170982
http://dx.doi.org/10.1016/j.rce.2014.05.020
_version_ 1783510513922080768
author Reina, J.
López-Causapé, C.
Rojo-Molinero, E.
Rubio, R.
author_facet Reina, J.
López-Causapé, C.
Rojo-Molinero, E.
Rubio, R.
author_sort Reina, J.
collection PubMed
description BACKGROUND AND OBJECTIVES: Acute respiratory infection is a very common condition in the general population. The majority of these infections are due to viruses. This study attempted to determine the clinical and epidemiological characteristics of adult patients with respiratory infection by the coronavirus OC43, NL63 and 229E. PATIENTS AND METHODS: Between January 2013 and February 2014, we prospectively studied all patients with suspected clinical respiratory infection by taking throat swabs and performing a reverse transcription polymerase chain reaction in search of coronavirus. RESULTS: In 48 cases (7.0% of the 686 enrolled patients; 12.6% of the 381 in whom a virus was detected) the presence of a coronavirus demonstrated. In 24 cases, the virus was OC43 (50%); in 14 cases, the virus was NL63 (29%); and in 10 cases, the virus was 229E (21%). The mean age was 54.5 years, with a slight predominance of men. The most common clinical presentations were nonspecific influenza symptoms (43.7%), pneumonia (29.2%) and chronic obstructive pulmonary disease exacerbation (8.3%). Fifty-two percent of the patients required hospitalization, and 2 patients required intensive care. There were no deaths. CONCLUSION: Acute respiratory infections caused by coronavirus mainly affect middle-aged male smokers, who are often affected by previous diseases. The most common clinical picture has been nonspecific influenza symptoms.
format Online
Article
Text
id pubmed-7094643
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher Elsevier España, S.L.U.
record_format MEDLINE/PubMed
spelling pubmed-70946432020-03-25 Características de las infecciones respiratorias agudas causadas por los coronavirus OC43, NL63 y 229E Reina, J. López-Causapé, C. Rojo-Molinero, E. Rubio, R. Rev Clin Esp Article BACKGROUND AND OBJECTIVES: Acute respiratory infection is a very common condition in the general population. The majority of these infections are due to viruses. This study attempted to determine the clinical and epidemiological characteristics of adult patients with respiratory infection by the coronavirus OC43, NL63 and 229E. PATIENTS AND METHODS: Between January 2013 and February 2014, we prospectively studied all patients with suspected clinical respiratory infection by taking throat swabs and performing a reverse transcription polymerase chain reaction in search of coronavirus. RESULTS: In 48 cases (7.0% of the 686 enrolled patients; 12.6% of the 381 in whom a virus was detected) the presence of a coronavirus demonstrated. In 24 cases, the virus was OC43 (50%); in 14 cases, the virus was NL63 (29%); and in 10 cases, the virus was 229E (21%). The mean age was 54.5 years, with a slight predominance of men. The most common clinical presentations were nonspecific influenza symptoms (43.7%), pneumonia (29.2%) and chronic obstructive pulmonary disease exacerbation (8.3%). Fifty-two percent of the patients required hospitalization, and 2 patients required intensive care. There were no deaths. CONCLUSION: Acute respiratory infections caused by coronavirus mainly affect middle-aged male smokers, who are often affected by previous diseases. The most common clinical picture has been nonspecific influenza symptoms. Elsevier España, S.L.U. 2014-12 2014-06-21 /pmc/articles/PMC7094643/ /pubmed/34170982 http://dx.doi.org/10.1016/j.rce.2014.05.020 Text en Copyright © 2014 Elsevier España, S.L.U. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Reina, J.
López-Causapé, C.
Rojo-Molinero, E.
Rubio, R.
Características de las infecciones respiratorias agudas causadas por los coronavirus OC43, NL63 y 229E
title Características de las infecciones respiratorias agudas causadas por los coronavirus OC43, NL63 y 229E
title_full Características de las infecciones respiratorias agudas causadas por los coronavirus OC43, NL63 y 229E
title_fullStr Características de las infecciones respiratorias agudas causadas por los coronavirus OC43, NL63 y 229E
title_full_unstemmed Características de las infecciones respiratorias agudas causadas por los coronavirus OC43, NL63 y 229E
title_short Características de las infecciones respiratorias agudas causadas por los coronavirus OC43, NL63 y 229E
title_sort características de las infecciones respiratorias agudas causadas por los coronavirus oc43, nl63 y 229e
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094643/
https://www.ncbi.nlm.nih.gov/pubmed/34170982
http://dx.doi.org/10.1016/j.rce.2014.05.020
work_keys_str_mv AT reinaj caracteristicasdelasinfeccionesrespiratoriasagudascausadasporloscoronavirusoc43nl63y229e
AT lopezcausapec caracteristicasdelasinfeccionesrespiratoriasagudascausadasporloscoronavirusoc43nl63y229e
AT rojomolineroe caracteristicasdelasinfeccionesrespiratoriasagudascausadasporloscoronavirusoc43nl63y229e
AT rubior caracteristicasdelasinfeccionesrespiratoriasagudascausadasporloscoronavirusoc43nl63y229e