Microbial drug discovery: 80 years of progress

Microbes have made a phenomenal contribution to the health and well-being of people throughout the world. In addition to producing many primary metabolites, such as amino acids, vitamins and nucleotides, they are capable of making secondary metabolites, which constitute half of the pharmaceuticals o...

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Detalles Bibliográficos
Autores principales: Demain, Arnold L, Sanchez, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094699/
https://www.ncbi.nlm.nih.gov/pubmed/19132062
http://dx.doi.org/10.1038/ja.2008.16
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author Demain, Arnold L
Sanchez, Sergio
author_facet Demain, Arnold L
Sanchez, Sergio
author_sort Demain, Arnold L
collection PubMed
description Microbes have made a phenomenal contribution to the health and well-being of people throughout the world. In addition to producing many primary metabolites, such as amino acids, vitamins and nucleotides, they are capable of making secondary metabolites, which constitute half of the pharmaceuticals on the market today and provide agriculture with many essential products. This review centers on these beneficial secondary metabolites, the discovery of which goes back 80 years to the time when penicillin was discovered by Alexander Fleming.
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spelling pubmed-70946992020-03-26 Microbial drug discovery: 80 years of progress Demain, Arnold L Sanchez, Sergio J Antibiot (Tokyo) Article Microbes have made a phenomenal contribution to the health and well-being of people throughout the world. In addition to producing many primary metabolites, such as amino acids, vitamins and nucleotides, they are capable of making secondary metabolites, which constitute half of the pharmaceuticals on the market today and provide agriculture with many essential products. This review centers on these beneficial secondary metabolites, the discovery of which goes back 80 years to the time when penicillin was discovered by Alexander Fleming. Nature Publishing Group UK 2009-01-09 2009 /pmc/articles/PMC7094699/ /pubmed/19132062 http://dx.doi.org/10.1038/ja.2008.16 Text en © Japan Antibiotics Research Association 2009 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Demain, Arnold L
Sanchez, Sergio
Microbial drug discovery: 80 years of progress
title Microbial drug discovery: 80 years of progress
title_full Microbial drug discovery: 80 years of progress
title_fullStr Microbial drug discovery: 80 years of progress
title_full_unstemmed Microbial drug discovery: 80 years of progress
title_short Microbial drug discovery: 80 years of progress
title_sort microbial drug discovery: 80 years of progress
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094699/
https://www.ncbi.nlm.nih.gov/pubmed/19132062
http://dx.doi.org/10.1038/ja.2008.16
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