Unexpected Cardiac Death During Anaesthesia of a Young Rabbit Associated with Fibro-fatty Replacement of the Right Ventricular Myocardium

A 6-month-old female pet rabbit was presented for routine ovariectomy. The pre-anaesthetic evaluation was unremarkable and no anaesthetic complications occurred during the procedure. However, at the end of the surgery, the rabbit suddenly showed acute bradycardia and cardiac death. Necropsy examinat...

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Autores principales: Romanucci, M., Defourny, S.V.P., Massimini, M., Valerii, V., Arbuatti, A., Giordano, V., Bongiovanni, L., Perrone, C., Della Salda, L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2017
Materias:
Spontaneously Arising Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094708/
https://www.ncbi.nlm.nih.gov/pubmed/27894597
http://dx.doi.org/10.1016/j.jcpa.2016.10.008
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author Romanucci, M.
Defourny, S.V.P.
Massimini, M.
Valerii, V.
Arbuatti, A.
Giordano, V.
Bongiovanni, L.
Perrone, C.
Della Salda, L.
author_facet Romanucci, M.
Defourny, S.V.P.
Massimini, M.
Valerii, V.
Arbuatti, A.
Giordano, V.
Bongiovanni, L.
Perrone, C.
Della Salda, L.
author_sort Romanucci, M.
collection PubMed
description A 6-month-old female pet rabbit was presented for routine ovariectomy. The pre-anaesthetic evaluation was unremarkable and no anaesthetic complications occurred during the procedure. However, at the end of the surgery, the rabbit suddenly showed acute bradycardia and cardiac death. Necropsy examination revealed marked dilation of the right ventricle, associated with diffuse thinning of the right ventricular free wall. Gross and histopathological findings were suggestive of a congenital dilated cardiomyopathy characterized by fibro-fatty replacement of the right ventricular myocardium. Similar myocardial lesions have not been previously described in rabbits, although they have been documented in myocardial diseases of man, dogs, cats, cattle, horses and chimpanzees.
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spelling pubmed-70947082020-03-25 Unexpected Cardiac Death During Anaesthesia of a Young Rabbit Associated with Fibro-fatty Replacement of the Right Ventricular Myocardium Romanucci, M. Defourny, S.V.P. Massimini, M. Valerii, V. Arbuatti, A. Giordano, V. Bongiovanni, L. Perrone, C. Della Salda, L. J Comp Pathol Spontaneously Arising Disease A 6-month-old female pet rabbit was presented for routine ovariectomy. The pre-anaesthetic evaluation was unremarkable and no anaesthetic complications occurred during the procedure. However, at the end of the surgery, the rabbit suddenly showed acute bradycardia and cardiac death. Necropsy examination revealed marked dilation of the right ventricle, associated with diffuse thinning of the right ventricular free wall. Gross and histopathological findings were suggestive of a congenital dilated cardiomyopathy characterized by fibro-fatty replacement of the right ventricular myocardium. Similar myocardial lesions have not been previously described in rabbits, although they have been documented in myocardial diseases of man, dogs, cats, cattle, horses and chimpanzees. Elsevier Ltd. 2017-01 2016-11-25 /pmc/articles/PMC7094708/ /pubmed/27894597 http://dx.doi.org/10.1016/j.jcpa.2016.10.008 Text en © 2016 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Spontaneously Arising Disease
Romanucci, M.
Defourny, S.V.P.
Massimini, M.
Valerii, V.
Arbuatti, A.
Giordano, V.
Bongiovanni, L.
Perrone, C.
Della Salda, L.
Unexpected Cardiac Death During Anaesthesia of a Young Rabbit Associated with Fibro-fatty Replacement of the Right Ventricular Myocardium
title Unexpected Cardiac Death During Anaesthesia of a Young Rabbit Associated with Fibro-fatty Replacement of the Right Ventricular Myocardium
title_full Unexpected Cardiac Death During Anaesthesia of a Young Rabbit Associated with Fibro-fatty Replacement of the Right Ventricular Myocardium
title_fullStr Unexpected Cardiac Death During Anaesthesia of a Young Rabbit Associated with Fibro-fatty Replacement of the Right Ventricular Myocardium
title_full_unstemmed Unexpected Cardiac Death During Anaesthesia of a Young Rabbit Associated with Fibro-fatty Replacement of the Right Ventricular Myocardium
title_short Unexpected Cardiac Death During Anaesthesia of a Young Rabbit Associated with Fibro-fatty Replacement of the Right Ventricular Myocardium
title_sort unexpected cardiac death during anaesthesia of a young rabbit associated with fibro-fatty replacement of the right ventricular myocardium
topic Spontaneously Arising Disease
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094708/
https://www.ncbi.nlm.nih.gov/pubmed/27894597
http://dx.doi.org/10.1016/j.jcpa.2016.10.008
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