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CD20 is dispensable for B-cell receptor signaling but is required for proper actin polymerization, adhesion and migration of malignant B cells

Surface protein CD20 serves as the critical target of immunotherapy in various B-cell malignancies for decades, however its biological function and regulation remain largely elusive. Better understanding of CD20 function may help to design improved rational therapies to prevent development of resist...

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Detalles Bibliográficos
Autores principales: Kozlova, Veronika, Ledererova, Aneta, Ladungova, Adriana, Peschelova, Helena, Janovska, Pavlina, Slusarczyk, Aleksander, Domagala, Joanna, Kopcil, Pavel, Vakulova, Viera, Oppelt, Jan, Bryja, Vitezslav, Doubek, Michael, Mayer, Jiri, Pospisilova, Sarka, Smida, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094844/
https://www.ncbi.nlm.nih.gov/pubmed/32210425
http://dx.doi.org/10.1371/journal.pone.0229170